Characterisation of pharmacogenomic variation in the Shetland and Orkney Isles in Scotland

Genetic variation is partly responsible for variability in drug response across populations. However, the full catalogue of pharmacogenetic variants and their distribution are yet to be established, thus posing challenges in implementing individualised medicine in understudied populations. This stud...

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Vydáno v:	Scientific reports Ročník 15; číslo 1; s. 42240 - 14
Hlavní autoři:	Twesigomwe, David, Aitman, Timothy J., Wilson, James F.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London Nature Publishing Group UK 26.11.2025 Nature Publishing Group Nature Portfolio
Témata:	631/154/436/434 631/208/726/649/2157 631/208/726/649/2219 631/208/728 692/700/228/2050/1512 ADME Alleles Cross-sectional studies Datasets Drug response Gene Frequency Genes Genetic diversity Genetic Variation Genomes Haplotypes Humanities and Social Sciences Humans Metabolism multidisciplinary Nucleotide sequence Pharmacogenetics Pharmacogenomic Variants Pharmacogenomics Population genetics Population studies Precision medicine Research ethics Science Science (multidisciplinary) Scotland Scottish Isles Star alleles Scotland United Kingdom > UK Haplotypes Drug response Phenotypes ADME Very important pharmacogenes Scottish Isles Star alleles Pharmacogenomics
ISSN:	2045-2322, 2045-2322
On-line přístup:	Získat plný text
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