Role of mobile genetic elements in the global dissemination of the carbapenem resistance gene bla NDM

The mobile resistance gene bla encodes the NDM enzyme which hydrolyses carbapenems, a class of antibiotics used to treat some of the most severe bacterial infections. The bla gene is globally distributed across a variety of Gram-negative bacteria on multiple plasmids, typically located within highly...

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Bibliographic Details

Published in:	Nature communications Vol. 13; no. 1; pp. 1131 - 13
Main Authors:	Acman, Mislav, Wang, Ruobing, van Dorp, Lucy, Shaw, Liam P, Wang, Qi, Luhmann, Nina, Yin, Yuyao, Sun, Shijun, Chen, Hongbin, Wang, Hui, Balloux, Francois
Format:	Journal Article
Language:	English
Published:	England Nature Portfolio 01.12.2022
Subjects:	Anti-Bacterial Agents - pharmacology beta-Lactamases - genetics beta-Lactamases - metabolism Carbapenems - pharmacology Interspersed Repetitive Sequences - genetics Microbial Sensitivity Tests Plasmids - genetics
ISSN:	2041-1723
Online Access:	Get full text
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