Variability in the analysis of a single neuroimaging dataset by many teams

Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses 1...

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Veröffentlicht in:Nature (London) Jg. 582; H. 7810; S. 84 - 88
Hauptverfasser: Botvinik-Nezer, Rotem, Holzmeister, Felix, Camerer, Colin F., Dreber, Anna, Johannesson, Magnus, Kirchler, Michael, Iwanir, Roni, Avesani, Paolo, Baczkowski, Blazej M., Bakst, Leah, Ball, Sheryl, Bault, Nadège, Beaton, Derek, Berkers, Ruud M. W. J., Biswal, Bharat B., Bortolini, Tiago, Bowring, Alexander, Braem, Senne, Brooks, Hayley R., Brudner, Emily G., Calderon, Cristian B., Camilleri, Julia A., Castrellon, Jaime J., Dadi, Kamalaker, Davis, Charles P., Luca, Alberto De, Delgado, Mauricio R., Demetriou, Lysia, Dennison, Jeffrey B., Dickie, Erin W., Dobryakova, Ekaterina, Dukart, Juergen, Duncan, Niall W., Fricke, G. Matthew, Fu, Shiguang, Genon, Sarah, Glatard, Tristan, Golowin, Sergej A. E., Gorgolewski, Krzysztof J., Guassi Moreira, João F., Harry, Bronson B., Herholz, Peer, Herman, Gabrielle, Hoffstaedter, Felix, Huettel, Scott A., Hughes, Matthew E., Iordan, Alexandru D., Isager, Peder M., Isik, Ayse I., Joseph, Michael J. E., Juliano, Anthony C., Kassinopoulos, Michalis, Koba, Cemal, Koscik, Timothy R., Kuhl, Brice A., Lauharatanahirun, Nina, Lee, Hongmi, Leemans, Alexander, Li, Monica Y. C., Liphardt, Schuyler W., Losecaat Vermeer, Annabel B., Mack, Michael L., Malpica, Norberto, Melero, Helena, Meyer, Benjamin, Meyer, Kristin N., Mihai, Glad, Nilsonne, Gustav, Notter, Michael P., Onicas, Adrian I., Papale, Paolo, Pérez, Alexandre, Pischedda, Doris, Reynolds, Richard C., Ricciardi, Emiliano, Rieck, Jenny R., Schlichting, Margaret L., Sheridan, Margaret A., Skagerlund, Kenny, Smith, Alec, Sokol-Hessner, Peter, Tashjian, Sarah M., Tisdall, Loreen, Tozzi, Leonardo, Turella, Luca, Vijayarajah, Sagana, Weeda, Wouter D., White, David J., Wisniewski, David, Xifra-Porxas, Alba, Yearling, Emily A., Yoon, Sangsuk, Yuan, Rui, Yuen, Kenneth S. L., Zhang, Lei, Zhang, Xu, Zosky, Joshua E., Nichols, Thomas E., Poldrack, Russell A., Schonberg, Tom
Format: Journal Article
Sprache:Englisch
Veröffentlicht: London Nature Publishing Group UK 04.06.2020
Nature Publishing Group
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ISSN:0028-0836, 1476-4687, 1476-4687
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Abstract Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses 1 . The flexibility of analytical approaches is exemplified by the fact that no two teams chose identical workflows to analyse the data. This flexibility resulted in sizeable variation in the results of hypothesis tests, even for teams whose statistical maps were highly correlated at intermediate stages of the analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Notably, a meta-analytical approach that aggregated information across teams yielded a significant consensus in activated regions. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset 2 – 5 . Our findings show that analytical flexibility can have substantial effects on scientific conclusions, and identify factors that may be related to variability in the analysis of functional magnetic resonance imaging. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for performing and reporting multiple analyses of the same data. Potential approaches that could be used to mitigate issues related to analytical variability are discussed. The results obtained by seventy different teams analysing the same functional magnetic resonance imaging dataset show substantial variation, highlighting the influence of analytical choices and the importance of sharing workflows publicly and performing multiple analyses.
AbstractList Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses.sup.1. The flexibility of analytical approaches is exemplified by the fact that no two teams chose identical workflows to analyse the data. This flexibility resulted in sizeable variation in the results of hypothesis tests, even for teams whose statistical maps were highly correlated at intermediate stages of the analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Notably, a meta-analytical approach that aggregated information across teams yielded a significant consensus in activated regions. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset.sup.2-5. Our findings show that analytical flexibility can have substantial effects on scientific conclusions, and identify factors that may be related to variability in the analysis of functional magnetic resonance imaging. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for performing and reporting multiple analyses of the same data. Potential approaches that could be used to mitigate issues related to analytical variability are discussed.
Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses1. The flexibility of analytical approaches is exemplified by the fact that no two teams chose identical workflows to analyse the data. This flexibility resulted in sizeable variation in the results of hypothesis tests, even for teams whose statistical maps were highly correlated at intermediate stages of the analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Notably, a meta-analytical approach that aggregated information across teams yielded a significant consensus in activated regions. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset2-5. Our findings show that analytical flexibility can have substantial effects on scientific conclusions, and identify factors that may be related to variability in the analysis of functional magnetic resonance imaging. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for performing and reporting multiple analyses of the same data. Potential approaches that could be used to mitigate issues related to analytical variability are discussed.
Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses.sup.1. The flexibility of analytical approaches is exemplified by the fact that no two teams chose identical workflows to analyse the data. This flexibility resulted in sizeable variation in the results of hypothesis tests, even for teams whose statistical maps were highly correlated at intermediate stages of the analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Notably, a meta-analytical approach that aggregated information across teams yielded a significant consensus in activated regions. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset.sup.2-5. Our findings show that analytical flexibility can have substantial effects on scientific conclusions, and identify factors that may be related to variability in the analysis of functional magnetic resonance imaging. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for performing and reporting multiple analyses of the same data. Potential approaches that could be used to mitigate issues related to analytical variability are discussed. The results obtained by seventy different teams analysing the same functional magnetic resonance imaging dataset show substantial variation, highlighting the influence of analytical choices and the importance of sharing workflows publicly and performing multiple analyses.
Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses . The flexibility of analytical approaches is exemplified by the fact that no two teams chose identical workflows to analyse the data. This flexibility resulted in sizeable variation in the results of hypothesis tests, even for teams whose statistical maps were highly correlated at intermediate stages of the analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Notably, a meta-analytical approach that aggregated information across teams yielded a significant consensus in activated regions. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset . Our findings show that analytical flexibility can have substantial effects on scientific conclusions, and identify factors that may be related to variability in the analysis of functional magnetic resonance imaging. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for performing and reporting multiple analyses of the same data. Potential approaches that could be used to mitigate issues related to analytical variability are discussed.
Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses1. The flexibility of analytical approaches is exemplified by the fact that no two teams chose identical workflows to analyse the data. This flexibility resulted in sizeable variation in the results of hypothesis tests, even for teams whose statistical maps were highly correlated at intermediate stages of the analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Notably, a meta-analytical approach that aggregated information across teams yielded a significant consensus in activated regions. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset2-5. Our findings show that analytical flexibility can have substantial effects on scientific conclusions, and identify factors that may be related to variability in the analysis of functional magnetic resonance imaging. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for performing and reporting multiple analyses of the same data. Potential approaches that could be used to mitigate issues related to analytical variability are discussed.Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses1. The flexibility of analytical approaches is exemplified by the fact that no two teams chose identical workflows to analyse the data. This flexibility resulted in sizeable variation in the results of hypothesis tests, even for teams whose statistical maps were highly correlated at intermediate stages of the analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Notably, a meta-analytical approach that aggregated information across teams yielded a significant consensus in activated regions. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset2-5. Our findings show that analytical flexibility can have substantial effects on scientific conclusions, and identify factors that may be related to variability in the analysis of functional magnetic resonance imaging. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for performing and reporting multiple analyses of the same data. Potential approaches that could be used to mitigate issues related to analytical variability are discussed.
Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses1. The flexibility of analytical approaches is exemplified by the fact that no two teams chose identical workflows to analyse the data. This flexibility resulted in sizeable variation in the results of hypothesis tests, even for teams whose statistical maps were highly correlated at intermediate stages ofthe analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Notably, a meta-analytical approach that aggregated information across teams yielded a significant consensus in activated regions. Furthermore, prediction markets ofresearchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset2-5. Our findings show that analytical flexibility can have substantial effects on scientific conclusions, and identify factors that may be related to variability in the analysis of functional magnetic resonance imaging. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for performing and reporting multiple analyses of the same data. Potential approaches that could be used to mitigate issues related to analytical variability are discussed.
Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses(1). The flexibility of analytical approaches is exemplified by the fact that no two teams chose identical workflows to analyse the data. This flexibility resulted in sizeable variation in the results of hypothesis tests, even for teams whose statistical maps were highly correlated at intermediate stages of the analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Notably, a meta-analytical approach that aggregated information across teams yielded a significant consensus in activated regions. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset(2-5). Our findings show that analytical flexibility can have substantial effects on scientific conclusions, and identify factors that may be related to variability in the analysis of functional magnetic resonance imaging. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for performing and reporting multiple analyses of the same data. Potential approaches that could be used to mitigate issues related to analytical variability are discussed. The results obtained by seventy different teams analysing the same functional magnetic resonance imaging dataset show substantial variation, highlighting the influence of analytical choices and the importance of sharing workflows publicly and performing multiple analyses.
Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses 1 . The flexibility of analytical approaches is exemplified by the fact that no two teams chose identical workflows to analyse the data. This flexibility resulted in sizeable variation in the results of hypothesis tests, even for teams whose statistical maps were highly correlated at intermediate stages of the analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Notably, a meta-analytical approach that aggregated information across teams yielded a significant consensus in activated regions. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset 2 – 5 . Our findings show that analytical flexibility can have substantial effects on scientific conclusions, and identify factors that may be related to variability in the analysis of functional magnetic resonance imaging. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for performing and reporting multiple analyses of the same data. Potential approaches that could be used to mitigate issues related to analytical variability are discussed. The results obtained by seventy different teams analysing the same functional magnetic resonance imaging dataset show substantial variation, highlighting the influence of analytical choices and the importance of sharing workflows publicly and performing multiple analyses.
Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses(1). The flexibility of analytical approaches is exemplified by the fact that no two teams chose identical workflows to analyse the data. This flexibility resulted in sizeable variation in the results of hypothesis tests, even for teams whose statistical maps were highly correlated at intermediate stages of the analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Notably, a meta-analytical approach that aggregated information across teams yielded a significant consensus in activated regions. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset(2-5). Our findings show that analytical flexibility can have substantial effects on scientific conclusions, and identify factors that may be related to variability in the analysis of functional magnetic resonance imaging. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for performing and reporting multiple analyses of the same data. Potential approaches that could be used to mitigate issues related to analytical variability are discussed.
Data analysis workflows in many scientific domains have become increasingly complex and flexible. To assess the impact of this flexibility on functional magnetic resonance imaging (fMRI) results, the same dataset was independently analyzed by 70 teams, testing nine ex-ante hypotheses1. The flexibility of analytic approaches is exemplified by the fact that no two teams chose identical workflows to analyze the data. This flexibility resulted in sizeable variation in hypothesis test results, even for teams whose statistical maps were highly correlated at intermediate stages of their analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Importantly, a meta-analytic approach that aggregated information across teams yielded significant consensus in activated regions across teams. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset2-5. Our findings show that analytic flexibility can have substantial effects on scientific conclusions, and demonstrate factors possibly related to variability in fMRI. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for multiple analyses of the same data. Potential approaches to mitigate issues related to analytical variability are discussed.
Audience Academic
Author Dickie, Erin W.
Sanz-Morales, Emilio
Baczkowski, Blazej M.
Green, Mikella A.
Lintz, Evan N.
Ray, Shruti
Sokol-Hessner, Peter
Huber, Juergen
Pischedda, Doris
Melero, Helena
Schultz, Douglas H.
Adcock, R. Alison
Nichols, Thomas E.
Beitner, Julia
Kong, Xiang-Zhen
Barilari, Marco
Notter, Michael P.
Poldrack, Russell A.
Herholz, Peer
Rodriguez-Thompson, Anais M.
Guassi Moreira, João F.
Galván, Adriana
Eickhoff, Simon B.
Bobadilla-Suarez, Sebastian
Tompson, Steven H.
Nilsonne, Gustav
Verguts, Tom
Glatard, Tristan
Bakst, Leah
Hu, Chuan-Peng
Collignon, Olivier
Fontanesi, Laura
Brooks, Hayley R.
Salo, Taylor
Dukart, Juergen
McGuire, Joseph T.
Dreber, Anna
Johnson, Matthew R.
Hughes, Matthew E.
Poline, Jean-Baptiste
Harry, Bronson B.
Holmes, Susan
McDonald, Kelsey
Glerean, Enrico
Zosky, Joshua E.
Meyer, Benjamin
Berkers, Ruud M. W. J.
Jahn, Andrew
Shen, Qiang
Camerer, Colin F.
Bajracharya, Aahana
Fricke, G. Matthew
Yuan, Rui
Romyn, Anthony
Maumet, Camille
Thirion, Bertrand
Biswal, Bharat B.
Kirchler, Michael
Donnat, Claire L.
Davis, Charles P.
Gau, Remi
J
AuthorAffiliation 24 Max Planck Research Group: Adaptive Memory, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
150 University of Pennsylvania, PA, USA
48 PROVIDI Lab, Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands
119 Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
71 Rotman Research Institute, Baycrest Health Sciences Centre, Toronto, Ontario, Canada
39 Department of Psychology, University of Nebraska-Lincoln, Lincoln, NE, USA
31 Oxford Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Population Health, University of Oxford, UK
98 Department of PM&R, Rutgers New Jersey Medical School, Newark, NJ
5 HSS and CNS, California Institute of Technology, Pasadena CA, USA
61 Faculty of Psychology, University of Basel, Basel, Switzerland
96 Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands
114 Departamento de Psicobiologí
AuthorAffiliation_xml – name: 25 Department of Psychology, Rutgers University-Newark, Newark, NJ, USA
– name: 130 Henry H. Wheeler, Jr. Brain Imaging Center, Helen Wills Neuroscience Institute, University of California Berkeley, CA, USA
– name: 57 Graduate Institute of Mind, Brain and Consciousness, Taipei Medical University, Taipei, Taiwan
– name: 137 Center for Social and Affective Neuroscience, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden
– name: 13 Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
– name: 21 Rotman Research Institute, Baycrest Health Sciences, Toronto, Canada
– name: 121 Department of Bioengineering, McGill University, QC, Canada
– name: 156 Centre for Human Psychopharmacology, Swinburne University, Hawthorn, VIC, Australia
– name: 100 Faculty of Economics and Statistics, University of Innsbruck, Innsbruck, Austria
– name: 139 Cognitive Neuroscience, Institute of Neuroscience and Medicine (INM-3), Forschungszentrum Jülich, Jülich, Germany
– name: 88 fMRI Laboratory, University of Michigan, Ann Arbor, MI, USA
– name: 10 Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA
– name: 23 Department of Psychology, Scene Grammar Lab, Goethe University, Frankfurt am Main, Germany
– name: 40 Center for Mind and Brain Science, University of Trento, Trento, Italy
– name: 66 Department of Computer Science and Software Engineering, Concordia University, Montreal, QC, Canada
– name: 150 University of Pennsylvania, PA, USA
– name: 158 Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA
– name: 43 Institute of Medical Psychology, Goethe University, Frankfurt am Main, Germany
– name: 14 Department of Otolaryngology, Washington University in Saint Louis, Saint Louis, MO, USA
– name: 55 Center for Traumatic Brain Injury Research, Kessler Foundation, East Hanover, NJ, USA
– name: 81 Leibniz-institut für Resilienzforschung (LIR), Mainz, Germany
– name: 12 Center for Mind/Brain Sciences - CIMeC, University of Trento, Rovereto, Italy
– name: 37 Department of Psychology and Neuroscience, Duke University, Durham, NC, USA
– name: 54 Department of Psychiatry, University of Toronto, Canada
– name: 65 Department of Psychology, University of California, Los Angeles, Los Angeles, CA, USA
– name: 5 HSS and CNS, California Institute of Technology, Pasadena CA, USA
– name: 9 Center for Cognitive Neuroscience, Duke University, Durham, NC, USA
– name: 62 Computer Science Department, University of New Mexico, Albuquerque, NM, USA
– name: 53 Krembil Centre for Neuroinformatics, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada
– name: 76 McConnell Brain Imaging Centre, The Neuro (Montreal Neurological Institute-Hospital), Faculty of Medicine, McGill University, Montreal, QC, Canada
– name: 103 Vienna Cognitive Science Hub, University of Vienna, Vienna, Austria
– name: 126 Department of Vision & Cognition, Netherlands Institute for Neuroscience, Meibergdreef 47, 1105 BA, Amsterdam, The Netherlands
– name: 27 School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China
– name: 32 Department of Experimental Psychology, Ghent University, Ghent, Belgium
– name: 143 Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden
– name: 132 Scientific and Statistical Computing Core, National Institute of Mental Health, NIH, Bethesda, MD, USA
– name: 122 Data Science and Sharing Team, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
– name: 116 Neuroimaging Center (NIC), Focus Program Translational Neurosciences (FTN), Johannes Gutenberg University Medical Center Mainz, Germany
– name: 49 Section of Endocrinology & Investigative Medicine, Faculty of Medicine, Imperial College London, London, UK
– name: 142 Department of Management and Engineering, Linköping University, Linköping, Sweden
– name: 75 Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada
– name: 56 Department of Statistics, Stanford University, Stanford, CA, USA
– name: 114 Departamento de Psicobiología, División de Psicología, CES Cardenal Cisneros, Madrid, Spain
– name: 146 Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA
– name: 31 Oxford Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Population Health, University of Oxford, UK
– name: 90 School of Health Sciences, Swinburne University of Technology, Hawthorn, VIC, Australia
– name: 151 Department of Psychology and Neuroscience, Duke University, NC, USA
– name: 20 School of Psychology, University of Plymouth, Plymouth, UK
– name: 47 Connecticut Institute for the Brain and Cognitive Sciences, University of Connecticut, Storrs, CT, USA
– name: 91 Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada
– name: 39 Department of Psychology, University of Nebraska-Lincoln, Lincoln, NE, USA
– name: 34 Department of Psychology, University of Denver, Denver, CO, USA
– name: 16 Center for Systems Neuroscience, Boston University, Boston, MA, USA
– name: 79 Department of Psychology & Psychology Clinical Neuroscience Center, University of New Mexico, Albuquerque, NM, USA
– name: 123 Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
– name: 138 Department of Economics and School of Neuroscience, Virginia Tech, Blacksburg, VA USA
– name: 11 Neuroinformatics Laboratory, Fondazione Bruno Kessler, Trento, Italy
– name: 18 School of Neuroscience, Virginia Tech, Blacksburg, VA, USA
– name: 58 Brain and Consciousness Research Centre, TMU-ShuangHo Hospital, New Taipei City, Taiwan
– name: 109 Haskins Laboratories, New Haven, CT, USA
– name: 101 Department of Physics, Florida International University, Miami, Florida, USA
– name: 124 Department of Psychology, Stockholm University, Stockholm, Sweden
– name: 71 Rotman Research Institute, Baycrest Health Sciences Centre, Toronto, Ontario, Canada
– name: 131 Department of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, USA
– name: 145 Department of Psychology, Stanford University, Stanford, CA, USA
– name: 2 Faculty of Life Sciences, Department of Neurobiology, Tel Aviv University, Israel
– name: 97 University of Iowa Carver College of Medicine, Department of Psychiatry, Iowa City, IA, USA
– name: 15 Department of Psychological and Brain Sciences, Boston University, Boston, MA, USA
– name: 22 Department of Psychology, Psychological Methods, University of Amsterdam, Amsterdam, The Netherlands
– name: 99 Department of Psychology, University of Oregon, Eugene, OR, USA
– name: 29 D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil
– name: 148 US Combat Capabilities Development Command Army Research Laboratory, USA
– name: 110 Biology Department, University of New Mexico, Albuquerque, NM, USA
– name: 6 Department of Economics, Stockholm School of Economics, Stockholm, Sweden
– name: 3 Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH, USA
– name: 35 Institute of Neuroscience and Medicine (INM-7: Brain and Behaviour), Research Centre Juelich, Juelich, Germany
– name: 93 Department of Psychology, University of Pennsylvania, Philadelphia, PA, USA
– name: 136 Department of Behavioural Sciences and Learning, Linköping University, Linköping, Sweden
– name: 86 Department of Industrial Engineering & Innovation Sciences, Eindhoven University of Technology, Eindhoven, The Netherlands
– name: 113 Inria, Univ Rennes, CNRS, Inserm, IRISA UMR 6074, Empenn ERL U 1228, Rennes, France
– name: 129 NeuroMI - Milan Center for Neuroscience, Milan, Italy
– name: 48 PROVIDI Lab, Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands
– name: 112 Laboratorio de Análisis de Imagen Médica y Biometría (LAIMBIO), Universidad Rey Juan Carlos, Madrid, Spain
– name: 102 Department of Cognition, Emotion, and Methods in Psychology, Faculty of Psychology, University of Vienna, Vienna, Austria
– name: 68 Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands
– name: 46 Brain Imaging Research Center, University of Connecticut, Storrs, CT, USA
– name: 140 Inria, CEA, Université Paris-Saclay, France
– name: 157 Department of Management and Marketing, School of Business, University of Dayton, Dayton, OH, USA
– name: 159 Biomedical Engineering Department, University of Connecticut, Storrs, CT, USA
– name: 117 Leibniz-Institut für Resilienzforschung (LIR), Mainz, Germany
– name: 120 Technische Universität Dresden, Germany
– name: 152 Center for Cognitive Neuroscience, Duke University, NC, USA
– name: 87 Neuroscience Department, Max Planck Institute for Empirical Aesthetics, Frankfurt am Main, Germany
– name: 42 Department of Psychology, University of Toronto, Toronto, ON, Canada
– name: 135 Department of Psychology and Neuroscience, University of North Carolina, Chapel Hill, NC, USA
– name: 82 The Department of Psychology and Neuroscience, Duke University, Durham, NC, USA
– name: 119 Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
– name: 118 Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
– name: 104 U.S. CCDC Army Research Laboratory, Human Research and Engineering Directorate, Aberdeen Proving Ground, MD, USA
– name: 107 Fralin Biomedical Research Institute, Roanoke, VA, USA
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  givenname: Rotem
  orcidid: 0000-0003-2669-1877
  surname: Botvinik-Nezer
  fullname: Botvinik-Nezer, Rotem
  organization: Sagol School of Neuroscience, Tel Aviv University, Department of Neurobiology, The George S. Wise Faculty of Life Sciences, Tel Aviv University, Department of Psychological and Brain Sciences, Dartmouth College
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  givenname: Felix
  orcidid: 0000-0001-9606-0427
  surname: Holzmeister
  fullname: Holzmeister, Felix
  organization: Department of Banking and Finance, University of Innsbruck
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  givenname: Colin F.
  orcidid: 0000-0003-4049-1871
  surname: Camerer
  fullname: Camerer, Colin F.
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  orcidid: 0000-0003-3989-9941
  surname: Dreber
  fullname: Dreber, Anna
  organization: Department of Economics, Stockholm School of Economics, Department of Economics, University of Innsbruck
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  givenname: Magnus
  orcidid: 0000-0001-8759-6393
  surname: Johannesson
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  organization: Department of Economics, Stockholm School of Economics
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  surname: Kirchler
  fullname: Kirchler, Michael
  organization: Department of Banking and Finance, University of Innsbruck
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  givenname: Roni
  surname: Iwanir
  fullname: Iwanir, Roni
  organization: Sagol School of Neuroscience, Tel Aviv University, Department of Neurobiology, The George S. Wise Faculty of Life Sciences, Tel Aviv University
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  givenname: Paolo
  orcidid: 0000-0001-8943-8911
  surname: Avesani
  fullname: Avesani, Paolo
  organization: Neuroinformatics Laboratory, Fondazione Bruno Kessler, Center for Mind/Brain Sciences - CIMeC, University of Trento
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  givenname: Blazej M.
  orcidid: 0000-0001-9827-797X
  surname: Baczkowski
  fullname: Baczkowski, Blazej M.
  organization: Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences
– sequence: 14
  givenname: Leah
  orcidid: 0000-0003-2741-5532
  surname: Bakst
  fullname: Bakst, Leah
  organization: Department of Psychological and Brain Sciences, Boston University, Center for Systems Neuroscience, Boston University
– sequence: 15
  givenname: Sheryl
  surname: Ball
  fullname: Ball, Sheryl
  organization: Department of Economics, Virginia Tech, School of Neuroscience, Virginia Tech
– sequence: 17
  givenname: Nadège
  orcidid: 0000-0001-8244-6062
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  organization: School of Psychology, University of Plymouth
– sequence: 18
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– sequence: 21
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– sequence: 27
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– sequence: 28
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– sequence: 41
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– sequence: 43
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– sequence: 45
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  orcidid: 0000-0003-0190-7678
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– sequence: 135
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– sequence: 142
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– sequence: 143
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– sequence: 162
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– sequence: 174
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– sequence: 176
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– sequence: 180
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– sequence: 183
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  organization: Department of Psychological Sciences, University of Connecticut, Brain Imaging Research Center, University of Connecticut, Connecticut Institute for the Brain and Cognitive Sciences, University of Connecticut
– sequence: 189
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  organization: Department of Management and Marketing, School of Business, University of Dayton
– sequence: 190
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  organization: Leibniz-Institut für Resilienzforschung (LIR), Neuroimaging Center (NIC), Focus Program Translational Neurosciences (FTN), Johannes Gutenberg University Medical Center Mainz
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  orcidid: 0000-0002-9586-595X
  surname: Zhang
  fullname: Zhang, Lei
  organization: Department of Cognition, Emotion, and Methods in Psychology, Faculty of Psychology, University of Vienna
– sequence: 193
  givenname: Xu
  orcidid: 0000-0003-1988-7767
  surname: Zhang
  fullname: Zhang, Xu
  organization: Brain Imaging Research Center, University of Connecticut, Connecticut Institute for the Brain and Cognitive Sciences, University of Connecticut, Biomedical Engineering Department, University of Connecticut
– sequence: 194
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  orcidid: 0000-0002-1962-3633
  surname: Zosky
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  organization: Department of Psychology, University of Nebraska–Lincoln, Center for Brain, Biology and Behavior, University of Nebraska–Lincoln
– sequence: 195
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  email: poldrack@stanford.edu
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– sequence: 197
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  fullname: Schonberg, Tom
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  organization: Sagol School of Neuroscience, Tel Aviv University, Department of Neurobiology, The George S. Wise Faculty of Life Sciences, Tel Aviv University
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Author contributions NARPS management team: R. Botvinik-Nezer, F. Holzmeister, C.F. Camerer, A. Dreber, J. Huber, M. Johannesson, M. Kirchler, R.A. Poldrack and T. Schonberg.fMRI dataset- experiment design: R. Iwanir, J. Durnez, R.A. Poldrack and T. Schonberg.fMRI dataset- data collection: R. Iwanir and T. Schonberg.fMRI dataset- preprocessing, quality assurance and data sharing: R. Botvinik-Nezer, K. Gorgolewski, R.A. Poldrack and T. Schonberg.Analysis teams- recruitment, point of contact and management: R. Botvinik-Nezer, R.A. Poldrack and T. Schonberg.Analysis teams- analysis of the submitted results and statistical maps: R.A. Poldrack, T.E. Nichols, J.A. Mumford, J-.B. Poline, A. Perez, R. Botvinik-Nezer, and T. Schonberg.Code review: T. Glatard. and K. Dadi.Prediction markets- design and management: F. Holzmeister, C.F. Camerer, A. Dreber, J. Huber, M. Johannesson and M. KirchlerPrediction markets- analysis: F. Holzmeister, R. Botvinik-Nezer, C.F. Camerer, A. Dreber, J. Huber, M. Johannesson, M. Kirchler, S. Kupek, R.A. Poldrack and T. Schonberg.Writing the manuscript: R. Botvinik-Nezer, F. Holzmeister, A. Dreber, J. Huber, M. Johannesson, M. Kirchler, T.E. Nichols, R.A. Poldrack and T. Schonberg.Participated as members of analysis teams and reviewed and edited the manuscript: R.A. Adcock, P. Avesani, B.M. Baczkowski, A. Bajracharya, L. Bakst, S. Ball, M. Barilari, N. Bault, D. Beaton, J. Beitner, R.G. Benoit, R.M.W.J. Berkers, J.P. Bhanji, B.B. Biswal, S. Bobadilla-Suarez, T. Bortolini, K.L. Bottenhorn, A. Bowring, S. Braem, H.R. Brooks, E.G. Brudner, C.B. Calderon, J.A. Camilleri, J.J. Castrellon, L. Cecchetti, E.C. Cieslik, Z.J. Cole, O. Collignon, R.W. Cox, W.A. Cunningham, S. Czoschke, K. Dadi, C.P. Davis, A. De Luca, M.R. Delgado, L. Demetriou, J.B. Dennison, X. Di, E.W. Dickie, E. Dobryakova, C.L. Donnat, J. Dukart, N.W. Duncan, A. Eed, S.B. Eickhoff, A. Erhart, L. Fontanesi, G.M. Fricke, S. Fu, A. Galván, R.i Gau, S. Genon, E. Glerean, J.J. Goeman, S.A.E. Golowin, C. González-García, K. J. Gorgolewski, C.L. Grady, M.A. Green, J.F. Guassi Moreira, O. Guest, S. Hakimi, J.P. Hamilton, R. Hancock, G. Handjaras, B.B. Harry, C. Hawco, P. Herholz, G. Herman, S. Heunis, F. Hoffstaedter, J. Hogeveen, S. Holmes, C.-P. Hu, S.A. Huettel, M.E. Hughes, V. Iacovella, A.D. Iordan, P.M. Isager, A.I. Isik, A. Jahn, M.R. Johnson, T. Johnstone, M.J.E. Joseph, A.C. Juliano, J.W. Kable, M. Kassinopoulos, C. Koba, X.-Z. Kong, T.R. Koscik, N.E. Kucukboyaci, B.A. Kuhl, A.R. Laird, C. Lamm, R. Langner, N. Lauharatanahirun, H. Lee, S. Lee, A. Leemans, A. Leo, E. Lesage, F. Li, M.Y.C. Li, P. Cheng Lim, E.N. Lintz, S.W. Liphardt, A.B. Losecaat Vermeer, B.C. Love, M.L. Mack, N. Malpica, T. Marins, C. Maumet, K. McDonald, J.T. McGuire, H. Melero, A.S. Méndez Leal, B. Meyer, K.N. Meyer, G. Mihai, G.D. Mitsis, J. Moll, D.M. Nielson, G. Nilsonne, M.P. Notter, E. Olivetti, A.I. Onicas, P. Papale, K.R. Patil, J.E. Peelle, D. Pischedda, Y. Prystauka, S. Ray, P.A. Reuter-Lorenz, R. C Reynolds, E. Ricciardi, J.R. Rieck, A.M. Rodriguez-Thompson , A. Romyn, T. Salo, G.R. Samanez-Larkin, E. Sanz-Morales, M.L. Schlichting, D.H. Schultz, Q. Shen, M.A. Sheridan, J.A. Silvers, K. Skagerlund, A. Smith, D.V. Smith, P. Sokol-Hessner, S.R. Steinkamp, S.M. Tashjian, B. Thirion, J.N. Thorp, G. Tinghög, L. Tisdall, S.H. Tompson, C. Toro-Serey, J.J. Torre Tresols, L. Tozzi, V. Truong, L. Turella, A.E. van 't Veer, T. Verguts, J.M. Vettel, S. Vijayarajah, K. Vo, M.B. Wall, W.D. Weeda, S. Weis, D.J. White, D. Wisniewski, A. Xifra-Porxas, E.A. Yearling, S. Yoon, R. Yuan, K.S.L. Yuen, L. Zhang, X. Zhang, J.E. Zosky
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Snippet Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results...
Data analysis workflows in many scientific domains have become increasingly complex and flexible. To assess the impact of this flexibility on functional...
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StartPage 84
SubjectTerms 59/36
59/57
631/378/2649/1409
631/477/2811
706/648
706/689/2788
Brain - diagnostic imaging
Brain - physiology
Brain mapping
Brain research
Cognitive science
Correlation analysis
Data Analysis
Data Science - methods
Data Science - standards
Datasets
Datasets as Topic - statistics & numerical data
Electronic data processing
Female
Flexibility
Functional magnetic resonance imaging
Functional Neuroimaging
Humanities and Social Sciences
Humans
Image processing
Logistic Models
Magnetic resonance
Magnetic Resonance Imaging
Male
Mathematical analysis
Medical imaging
Meta-Analysis as Topic
Methods
Models, Neurological
multidisciplinary
Neuroimaging
Neuroscience
Neurosciences & behavior
Neurosciences & comportement
Prediction markets
Psychology
psykologi
Reproducibility of Results
Research Personnel - organization & administration
Research Personnel - standards
Researchers
Science
Science (multidisciplinary)
Sciences sociales & comportementales, psychologie
Social & behavioral sciences, psychology
Software
Software packages
Teams
Technology application
Variability
Title Variability in the analysis of a single neuroimaging dataset by many teams
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https://www.ncbi.nlm.nih.gov/pubmed/32483374
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