Efficacy of Pneumococcal Nontypable Haemophilus influenzae Protein D Conjugate Vaccine (PHiD-CV) in Young Latin American Children: A Double-Blind Randomized Controlled Trial

The relationship between pneumococcal conjugate vaccine-induced antibody responses and protection against community-acquired pneumonia (CAP) and acute otitis media (AOM) is unclear. This study assessed the impact of the ten-valent pneumococcal nontypable Haemophilus influenzae protein D conjugate va...

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Bibliographic Details
Published in:	PLoS medicine Vol. 11; no. 6; p. e1001657
Main Authors:	Tregnaghi, Miguel W., Sáez-Llorens, Xavier, López, Pio, Abate, Hector, Smith, Enrique, Pósleman, Adriana, Calvo, Arlene, Wong, Digna, Cortes-Barbosa, Carlos, Ceballos, Ana, Tregnaghi, Marcelo, Sierra, Alexandra, Rodriguez, Mirna, Troitiño, Marisol, Carabajal, Carlos, Falaschi, Andrea, Leandro, Ana, Castrejón, Maria Mercedes, Lepetic, Alejandro, Lommel, Patricia, Hausdorff, William P., Borys, Dorota, Guiñazú, Javier Ruiz, Ortega-Barría, Eduardo, Yarzábal, Juan P., Schuerman, Lode
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 01.06.2014 Public Library of Science (PLoS)
Subjects:	Antibodies, Bacterial - blood Bacterial Proteins - immunology Biology and Life Sciences Carrier Proteins - immunology Child, Preschool Children & youth Clinical trials Demographic aspects Dosage and administration Double-Blind Method Drug therapy Haemophilus Infections - microbiology Haemophilus influenzae Haemophilus influenzae - immunology Health aspects Hemophilus influenzae Hispanic American children Humans Immunization, Secondary Immunoglobulin D - immunology Infant Influenza vaccines Intention to Treat Analysis Latin America Lipoproteins - immunology Medicine and health sciences Methods Otitis Media - immunology Otitis Media - microbiology Otitis Media - prevention & control Pneumococcal Infections - immunology Pneumococcal Infections - microbiology Pneumococcal Infections - prevention & control Pneumococcal Vaccines - immunology Pneumonia Research and Analysis Methods Streptococcus pneumoniae Streptococcus pneumoniae - immunology Studies Treatment Outcome Vaccination Vaccines Vaccines, Conjugate - immunology Latin America Argentina Panama
ISSN:	1549-1676, 1549-1277, 1549-1676
Online Access:	Get full text
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