Role of Brain-Derived Neurotrophic Factor in Beneficial Effects of Repetitive Transcranial Magnetic Stimulation for Upper Limb Hemiparesis after Stroke

Repetitive transcranial magnetic stimulation (rTMS) can improve upper limb hemiparesis after stroke but the mechanism underlying its efficacy remains elusive. rTMS seems to alter brain-derived neurotrophic factor (BDNF) and such effect is influenced by BDNF gene polymorphism. To investigate the mole...

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Bibliographic Details
Published in:	PloS one Vol. 11; no. 3; p. e0152241
Main Authors:	Niimi, Masachika, Hashimoto, Kenji, Kakuda, Wataru, Miyano, Satoshi, Momosaki, Ryo, Ishima, Tamaki, Abo, Masahiro
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 23.03.2016 Public Library of Science (PLoS)
Subjects:	Aged Arm Biology and Life Sciences Biomarkers Bipolar disorder Brain Brain research Brain-derived neurotrophic factor Brain-Derived Neurotrophic Factor - blood Brain-Derived Neurotrophic Factor - genetics Brain-Derived Neurotrophic Factor - physiology Brain-Derived Neurotrophic Factor/blood/genetics/physiology Care and treatment Case-Control Studies Complications and side effects Female Gelatinase B Gene polymorphism Health aspects Hemiplegia Human health sciences Human subjects Humans Magnetic brain stimulation Magnetic fields Male Matrix metalloproteinase Matrix Metalloproteinase 9 - blood Medicine Medicine and Health Sciences Mental depression Mental health Metalloproteinase Middle Aged Muscles Neurologie Neurology Neurosciences Paresis Paresis - etiology Paresis - physiopathology Paresis - rehabilitation Paresis - therapy Paresis/etiology/physiopathology/rehabilitation/therapy Patients Physical Sciences Polymorphism Polymorphism, Genetic - genetics Polymorphism, Genetic - physiology Polymorphism, Genetic/genetics/physiology Protein Precursors - blood Rehabilitation Research and Analysis Methods Risk factors Sciences de la santé humaine Serum levels Stroke Stroke - complications Studies Therapy Transcranial Direct Current Stimulation Transcranial magnetic stimulation
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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