Smoking, alcohol consumption, and cancer: A mendelian randomisation study in UK Biobank and international genetic consortia participants

Smoking is a well-established cause of lung cancer and there is strong evidence that smoking also increases the risk of several other cancers. Alcohol consumption has been inconsistently associated with cancer risk in observational studies. This mendelian randomisation (MR) study sought to investiga...

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Bibliographic Details
Published in:	PLoS medicine Vol. 17; no. 7; p. e1003178
Main Authors:	Larsson, Susanna C., Carter, Paul, Kar, Siddhartha, Vithayathil, Mathew, Mason, Amy M., Michaëlsson, Karl, Burgess, Stephen
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 23.07.2020 Public Library of Science (PLoS)
Subjects:	Addictive behaviors Alcohol Alcohol Drinking - genetics Alcohol use Analysis Biobanks Biological Specimen Banks Biology and Life Sciences Bladder cancer Breast cancer Cancer Cancer genetics Cancer research Cervix Colorectal cancer Consortia Drinking (Alcoholic beverages) Epidemiology Esophageal cancer Esophagus Female Gastric cancer Genetic aspects Genetic diversity Genetic Predisposition to Disease Genetic research Genome-Wide Association Study Genomes Genomics Head & neck cancer Head and neck cancer Health aspects Humans Inheritances Kidney cancer Lung cancer Male Medicine and Health Sciences Mendelian Randomization Analysis - methods Meta-analysis Methods Neoplasms - etiology Neoplasms - genetics Ovarian cancer Polymorphism, Single Nucleotide Primary care Prostate cancer Public health Research and Analysis Methods Risk factors Smoking Smoking - genetics Social Sciences Standard deviation Statistical analysis Stomach Studies United Kingdom White People - genetics United Kingdom United Kingdom > UK Sweden
ISSN:	1549-1676, 1549-1277, 1549-1676
Online Access:	Get full text
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