Identification of Circulating Tumor DNA for the Early Detection of Small-cell Lung Cancer

Circulating tumor DNA (ctDNA) is emerging as a key potential biomarker for post-diagnosis surveillance but it may also play a crucial role in the detection of pre-clinical cancer. Small-cell lung cancer (SCLC) is an excellent candidate for early detection given there are no successful therapeutic op...

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Veröffentlicht in:	EBioMedicine Jg. 10; H. C; S. 117 - 123
Hauptverfasser:	Fernandez-Cuesta, Lynnette, Perdomo, Sandra, Avogbe, Patrice H., Leblay, Noemie, Delhomme, Tiffany M., Gaborieau, Valerie, Abedi-Ardekani, Behnoush, Chanudet, Estelle, Olivier, Magali, Zaridze, David, Mukeria, Anush, Vilensky, Marta, Holcatova, Ivana, Polesel, Jerry, Simonato, Lorenzo, Canova, Cristina, Lagiou, Pagona, Brambilla, Christian, Brambilla, Elisabeth, Byrnes, Graham, Scelo, Ghislaine, Le Calvez-Kelm, Florence, Foll, Matthieu, McKay, James D., Brennan, Paul
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands Elsevier B.V 01.08.2016 Elsevier
Schlagworte:	Advanced Basic Science Biomarkers, Tumor Case-Control Studies cfDNA ctDNA DNA, Neoplasm - blood Early detection Early Detection of Cancer Female Humans Internal Medicine Leukocytes - metabolism Lung Neoplasms - blood Lung Neoplasms - diagnosis Lung Neoplasms - genetics Male Mutation Neoplasm Staging Research Paper Screening Small Cell Lung Carcinoma - blood Small Cell Lung Carcinoma - diagnosis Small Cell Lung Carcinoma - genetics Small-cell lung cancer TP53 mutations Tumor Suppressor Protein p53 - genetics Screening TP53 mutations Small-cell lung cancer cfDNA ctDNA Early detection
ISSN:	2352-3964, 2352-3964
Online-Zugang:	Volltext
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