Obesity and Multiple Sclerosis: A Mendelian Randomization Study

Observational studies have reported an association between obesity, as measured by elevated body mass index (BMI), in early adulthood and risk of multiple sclerosis (MS). However, bias potentially introduced by confounding and reverse causation may have influenced these findings. Therefore, we elect...

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Vydané v:	PLoS medicine Ročník 13; číslo 6; s. e1002053
Hlavní autori:	Mokry, Lauren E., Ross, Stephanie, Timpson, Nicholas J., Sawcer, Stephen, Davey Smith, George, Richards, J. Brent
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Public Library of Science 28.06.2016 Public Library of Science (PLoS)
Predmet:	Analysis Biology and Life Sciences Body Mass Index Complications and side effects Genome-Wide Association Study Humans Medicine and Health Sciences Mendelian Randomization Analysis Multiple sclerosis Multiple Sclerosis - etiology Obesity Obesity - complications Obesity - genetics Odds Ratio Polymorphism, Single Nucleotide Research and Analysis Methods Risk factors Social Sciences Studies Vitamin D
ISSN:	1549-1676, 1549-1277, 1549-1676
On-line prístup:	Získať plný text
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