Elevations in blood glucose before and after the appearance of islet autoantibodies in children

The etiology of type 1 diabetes has polygenic and environmental determinants that lead to autoimmune responses against pancreatic β cells and promote β cell death. The autoimmunity is considered silent without metabolic consequences until late preclinical stages,and it remains unknown how early in t...

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Bibliographic Details
Published in:	The Journal of clinical investigation Vol. 132; no. 20; pp. 1 - 10
Main Authors:	Warncke, Katharina, Weiss, Andreas, Achenbach, Peter, von dem Berge, Thekla, Berner, Reinhard, Casteels, Kristina, Groele, Lidia, Hatzikotoulas, Konstantinos, Hommel, Angela, Kordonouri, Olga, Elding Larsson, Helena, Lundgren, Markus, Marcus, Benjamin A., Snape, Matthew D., Szypowska, Agnieszka, Todd, John A., Bonifacio, Ezio, Ziegler, Anette-G.
Format:	Journal Article
Language:	English
Published:	United States American Society for Clinical Investigation 17.10.2022
Subjects:	Age Autoantibodies Autoimmunity Biomedical research Blood Glucose Blood sugar Body mass index Cell death Child Child, Preschool Children Clinical Medicine Development and progression Diabetes Diabetes mellitus (insulin dependent) Diabetes Mellitus, Type 1 Endocrinology and Diabetes Endokrinologi och diabetes Etiology Genetic Predisposition to Disease Genotype & phenotype Glucose Health aspects Health risk assessment Homeostasis Humans Immunology INS gene Insulin Islands of Langerhans Islets of Langerhans Klinisk medicin Measurement Medical and Health Sciences Medicin och hälsovetenskap Metabolism Pancreas Pathogenesis Pediatric research Physiological aspects Risk factors Seroconversion Type 1 diabetes Germany Insulin Immunology Diabetes
ISSN:	1558-8238, 0021-9738, 1558-8238
Online Access:	Get full text
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