Fragment Length of Circulating Tumor DNA

Malignant tumors shed DNA into the circulation. The transient half-life of circulating tumor DNA (ctDNA) may afford the opportunity to diagnose, monitor recurrence, and evaluate response to therapy solely through a non-invasive blood draw. However, detecting ctDNA against the normally occurring back...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS genetics Jg. 12; H. 7; S. e1006162
Hauptverfasser:	Underhill, Hunter R., Kitzman, Jacob O., Hellwig, Sabine, Welker, Noah C., Daza, Riza, Baker, Daniel N., Gligorich, Keith M., Rostomily, Robert C., Bronner, Mary P., Shendure, Jay
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 01.07.2016 Public Library of Science (PLoS)
Schlagworte:	Alleles Animals Biology and life sciences Biomarkers, Tumor - blood Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - metabolism Cell Line, Tumor Deoxyribonucleic acid DNA DNA sequencing DNA, Neoplasm - blood DNA, Neoplasm - genetics Experiments Genes Genetic aspects Glioblastoma - blood Glioblastoma - genetics Hep G2 Cells Humans Liver Neoplasms - genetics Liver Neoplasms - metabolism Lung cancer Lung Neoplasms - genetics Lung Neoplasms - metabolism Magnetic Resonance Imaging Male Medicine and Health Sciences Melanoma Melanoma - genetics Melanoma - metabolism Metastasis Methods Mutation Neoplasm Transplantation Proto-Oncogene Proteins B-raf - genetics Rats Research and Analysis Methods Studies Tumors
ISSN:	1553-7404, 1553-7390, 1553-7404
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!