Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death

The perpetuation of inflammation is an important pathophysiological contributor to the global medical burden. Chronic inflammation is promoted by non-programmed cell death 1 , 2 ; however, how inflammation is instigated, its cellular and molecular mediators, and its therapeutic value are poorly defi...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	Nature (London) Ročník 569; číslo 7755; s. 236 - 240
Hlavní autoři:	Silvestre-Roig, Carlos, Braster, Quinte, Wichapong, Kanin, Lee, Ernest Y., Teulon, Jean Marie, Berrebeh, Nihel, Winter, Janine, Adrover, José M., Santos, Giancarlo Santiago, Froese, Alexander, Lemnitzer, Patricia, Ortega-Gómez, Almudena, Chevre, Raphael, Marschner, Julian, Schumski, Ariane, Winter, Carla, Perez-Olivares, Laura, Pan, Chang, Paulin, Nicole, Schoufour, Tom, Hartwig, Helene, González-Ramos, Silvia, Kamp, Frits, Megens, Remco T. A., Mowen, Kerri A., Gunzer, Matthias, Maegdefessel, Lars, Hackeng, Tilman, Lutgens, Esther, Daemen, Mat, von Blume, Julia, Anders, Hans-Joachim, Nikolaev, Viacheslav O., Pellequer, Jean-Luc, Weber, Christian, Hidalgo, Andrés, Nicolaes, Gerry A. F., Wong, Gerard C. L., Soehnlein, Oliver
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London Nature Publishing Group UK 01.05.2019 Nature Publishing Group
Témata:	13/1 13/2 13/21 13/31 13/51 14 14/1 14/19 14/28 14/3 14/69 631/80/82 64/110 64/60 692/420/256/2515 692/699/75/593/2100 82/29 82/51 Animal models Animals Apoptosis Arteries - pathology Arteriosclerosis Artificial intelligence Atherosclerosis Atherosclerosis - pathology Biochemistry Cell adhesion & migration Cell Death Cell Membrane - drug effects Cell Membrane - metabolism Cellular Biology Chemokines Cytotoxicity Destabilization Disease Models, Animal Ejection Female Histone H4 Histones Histones - antagonists & inhibitors Histones - metabolism Humanities and Social Sciences Inflammation Inflammation - metabolism Inflammation - pathology Lesions Letter Leukocytes Leukocytes (neutrophilic) Life Sciences Lysis Mice Mice, Inbred C57BL Mortality multidisciplinary Muscles Myocytes, Smooth Muscle - pathology Neutralization Neutropenia Neutrophils Neutrophils - cytology Observations Open source software Peptides Physiological aspects Plaques Porosity Protein Binding - drug effects Proteins Science Science (multidisciplinary) Smooth muscle Vascular diseases Germany
ISSN:	0028-0836, 1476-4687, 1476-4687
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Buďte první, kdo okomentuje tento záznam!