GHOSTX: An Improved Sequence Homology Search Algorithm Using a Query Suffix Array and a Database Suffix Array

DNA sequences are translated into protein coding sequences and then further assigned to protein families in metagenomic analyses, because of the need for sensitivity. However, huge amounts of sequence data create the problem that even general homology search analyses using BLASTX become difficult in...

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Bibliographic Details
Published in:	PloS one Vol. 9; no. 8; p. e103833
Main Authors:	Suzuki, Shuji, Kakuta, Masanori, Ishida, Takashi, Akiyama, Yutaka
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 06.08.2014 Public Library of Science (PLoS)
Subjects:	Algorithms Alternating current Analysis Arrays Bioinformatics Biology and Life Sciences Computer applications Cost analysis Data bases Data processing Databases, Genetic Deoxyribonucleic acid DNA Downloading Engineering Gene sequencing Genomes Homology Information science Nucleotide sequence Protein families Proteins Queries Research and Analysis Methods Search algorithms Seeds Sensitivity Sensitivity analysis Sequence Alignment - methods Sequence Homology Software Japan
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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