Risk score for predicting mortality including urine lipoarabinomannan detection in hospital inpatients with HIV-associated tuberculosis in sub-Saharan Africa: Derivation and external validation cohort study

The prevalence of and mortality from HIV-associated tuberculosis (HIV/TB) in hospital inpatients in Africa remains unacceptably high. Currently, there is a lack of tools to identify those at high risk of early mortality who may benefit from adjunctive interventions. We therefore aimed to develop and...

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Bibliographic Details
Published in:	PLoS medicine Vol. 16; no. 4; p. e1002776
Main Authors:	Gupta-Wright, Ankur, Corbett, Elizabeth L., Wilson, Douglas, van Oosterhout, Joep J., Dheda, Keertan, Huerga, Helena, Peter, Jonny, Bonnet, Maryline, Alufandika-Moyo, Melanie, Grint, Daniel, Lawn, Stephen D., Fielding, Katherine
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 05.04.2019 Public Library of Science (PLoS)
Subjects:	Adult Africa Africa South of the Sahara - epidemiology AIDS-Related Opportunistic Infections AIDS-Related Opportunistic Infections - diagnosis AIDS-Related Opportunistic Infections - mortality AIDS-Related Opportunistic Infections - urine Anemia Antiretroviral agents Antiretroviral drugs Antiretroviral therapy Biology and Life Sciences Calibration Care and treatment CD4 antigen Clinical medicine Cohort analysis Cohort Studies Complications and side effects Drug resistance Drug therapy Epidemiology Fatalities Female Funding Health aspects Hemoglobin Hemoglobins Highly active antiretroviral therapy HIV HIV Infections HIV Infections - complications HIV Infections - diagnosis HIV Infections - mortality HIV Infections - urine HIV patients Hospital admission and discharge Hospital patients Hospitalization Hospitals Human health and pathology Human immunodeficiency virus Humans Hygiene Infections Infectious diseases Inpatients Life Sciences Lifesaving Lipoarabinomannan Lipopolysaccharides Lipopolysaccharides - urine Male Mass Screening Mass Screening - methods Median (statistics) Medical research Medicine Medicine and Health Sciences Meningitis Microbial drug resistance Morbidity Mortality Patient outcomes Patients Physical Sciences Pneumonia Prognosis Research and Analysis Methods Research Design Risk Factors Risk groups Santé publique et épidémiologie South of the Sahara Supervision Survival Analysis Tuberculosis Tuberculosis - diagnosis Tuberculosis - mortality Tuberculosis - urine Urinalysis Urine Africa South of the Sahara Sub-Saharan Africa United Kingdom > UK Malawi United States > US Africa South Africa France
ISSN:	1549-1676, 1549-1277, 1549-1676
Online Access:	Get full text
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