Functional Anatomy of Polycomb and Trithorax Chromatin Landscapes in Drosophila Embryos

Polycomb group (PcG) and trithorax group (trxG) proteins are conserved chromatin factors that regulate key developmental genes throughout development. In Drosophila, PcG and trxG factors bind to regulatory DNA elements called PcG and trxG response elements (PREs and TREs). Several DNA binding protei...

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Bibliographic Details
Published in:	PLoS biology Vol. 7; no. 1; p. e1000013
Main Authors:	Schuettengruber, Bernd, Ganapathi, Mythily, Leblanc, Benjamin, Portoso, Manuela, Jaschek, Rami, Tolhuis, Bas, van Lohuizen, Maarten, Tanay, Amos, Cavalli, Giacomo
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 01.01.2009 Public Library of Science (PLoS)
Subjects:	Animals Biochemistry, Molecular Biology Cell Biology Cell division Chromatin Chromatin - physiology Chromatin Immunoprecipitation Chromosomal Proteins, Non-Histone - physiology Chromosomes Classification Deoxyribonucleic acid Developmental Biology DNA Drosophila Drosophila melanogaster - embryology Drosophila Proteins - physiology Embryo Epigenetics Evaluation Gene expression Gene Expression Regulation, Developmental - physiology Genetic aspects Genetic regulation Genetics Genetics and Genomics Genomes Genomics Life Sciences Molecular Biology Ontology Polycomb Repressive Complex 1 Properties Protein binding Proteins Reverse Transcriptase Polymerase Chain Reaction United States Drosophila Proteins Chromatin Animals Polycomb Repressive Complex 1 Chromatin Immunoprecipitation Gene Expression Regulation, Developmental Chromosomal Proteins, Non-Histone Reverse Transcriptase Polymerase Chain Reaction Drosophila melanogaster
ISSN:	1545-7885, 1544-9173, 1545-7885
Online Access:	Get full text
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