Testosterone, Sex Hormone-Binding Globulin and the Metabolic Syndrome in Men: An Individual Participant Data Meta-Analysis of Observational Studies

Low total testosterone (TT) and sex hormone-binding globulin (SHBG) concentrations have been associated with the metabolic syndrome (MetS) in men, but the reported strength of association varies considerably. We aimed to investigate whether associations differ across specific subgroups (according to...

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Bibliographic Details
Published in:	PloS one Vol. 9; no. 7; p. e100409
Main Authors:	Brand, Judith S., Rovers, Maroeska M., Yeap, Bu B., Schneider, Harald J., Tuomainen, Tomi-Pekka, Haring, Robin, Corona, Giovanni, Onat, Altan, Maggio, Marcello, Bouchard, Claude, Tong, Peter C. Y., Chen, Richard Y. T., Akishita, Masahiro, Gietema, Jourik A., Gannagé-Yared, Marie-Hélène, Undén, Anna-Lena, Hautanen, Aarno, Goncharov, Nicolai P., Kumanov, Philip, Chubb, S. A. Paul, Almeida, Osvaldo P., Wittchen, Hans-Ulrich, Klotsche, Jens, Wallaschofski, Henri, Völzke, Henry, Kauhanen, Jussi, Salonen, Jukka T., Ferrucci, Luigi, van der Schouw, Yvonne T.
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 14.07.2014 Public Library of Science (PLoS)
Subjects:	Adult Age Factors Aged Aged, 80 and over Alcohol use Analysis Androgens Binding Biology and Life Sciences Body mass Body Mass Index Body size Body weight Cross-Sectional Studies Data analysis Data processing Epidemiology Globulins Health risks Hormones Humans Hyperglycemia Hypertension Hypertriglyceridemia Low concentrations Male Medical research Medicine and Health Sciences Men Meta-analysis Metabolic disorders Metabolic syndrome Metabolic Syndrome - epidemiology Middle Aged Obesity Observational studies Observational Studies as Topic Odds Ratio Overweight Physical Sciences Prospective Studies Research and Analysis Methods Sex Sex Hormone-Binding Globulin - analysis Subgroups Testosterone Testosterone - blood Upgrading Young Adult Istanbul Turkey Perth Western Australia Australia Singapore United States > US Netherlands Turkey China Finland Louisiana Hong Kong China Italy Australia Germany
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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