Directional dominance on stature and cognition in diverse human populations

An analysis of 16 health-related quantitative traits in approximately 350,000 individuals reveals statistically significant associations between genome-wide homozygosity and four complex traits (height, lung function, cognitive ability and educational attainment); in each case increased homozygosity...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	Nature (London) Ročník 523; číslo 7561; s. 459 - 462
Hlavní autoři:	Esko, Tonu, Nutile, Teresa, Jackson, Anne U., Schurmann, Claudia, Stančáková, Alena, Zhao, Wei, Enroth, Stefan, Guo, Xiuqing, Chasman, Daniel I., Rietveld, Cornelius A., Pattaro, Cristian, Vuckovic, Dragana, Bouchard, Claude, Benton, Miles C., Drong, Alexander, Yengo, Loic, Bielak, Lawrence F., Zhi, Degui, Mägi, Reedik, Karaderi, Tugce, Liu, Tian, van der Laan, Sander W., Asselbergs, Folkert W., Barr, R. Graham, Baumeister, Sebastian E., Benjamin, Daniel J., Boerwinkle, Eric, Chanock, Stephen J., Gillham-Nasenya, Irina, Gottesman, Omri, Grodstein, Francine, Gu, Charles, Huang, Jinyan, Ingelsson, Erik, Johansson, Åsa, Jukema, J. Wouter, Kähönen, Mika, Koellinger, Philipp, Kooner, Manraj K., Lahti, Jari, Lu, Yingchang, Lundqvist, Annamari, Männistö, Satu, Matchan, Angela, Mathias, Rasika A., Meitinger, Thomas, Morrison, Alanna, Nadukuru, Rajiv, Nelis, Mari, Nieminen, Markku S., Patarcic, Inga, Peyser, Patricia A., Prokopenko, Inga, Rose, Lynda M., Sala, Cinzia, Sarin, Antti-Pekka, Schmidt, Helena, Sennblad, Bengt, Seshadri, Sudha, Smith, Blair H., Smith, Jennifer A., Southam, Lorraine, Stathopoulou, Maria G., Strawbridge, Rona J., Taylor, Kent D., Tuomilehto, Jaakko, Vaidya, Dhananjay, Vasankari, Tuula, Vedantam, Sailaja, Vuoksimaa, Eero, Whitfield, John B., Willemsen, Gonneke, Zaza, Gianluigi, Melbye, Mads, Bisgaard, Hans, Cooper, Richard S., Froguel, Philippe, Pasterkamp, Gerard, Ferrucci, Luigi, Scott, Robert A., Morris, Andrew D., Deloukas, Panos, Lindgren, Cecilia M., Timpson, Nicholas J., Munroe, Patricia B., Gambaro, Giovanni, Morris, Andrew P., Eriksson, Johan G., Martin, Nicholas G., Hunt, Steven C., Kaprio, Jaakko, Becker, Diane M., Bharadwaj, Dwaipayan, Boehnke, Michael, Metspalu, Andres, Dupuis, Josée, Vollenweider, Peter, Rotter, Jerome I., Weir, David R., Chambers, John C.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London Nature Publishing Group UK 23.07.2015 Nature Publishing Group
Témata:	45 45/43 631/181/2474 631/208/729/743 631/208/730 Biological Evolution Blood pressure Blood Pressure - genetics Body Height - genetics Cholesterol, LDL - genetics Cognition Cognition & reasoning Cognitive ability Cohort Studies Disease Educational attainment Educational Status Female Forced Expiratory Volume - genetics Genetic research Genome, Human - genetics Genomes Genomics Homozygosity Homozygote Human populations Humanities and Social Sciences Humans Inbreeding letter Lung Volume Measurements Male multidisciplinary Offspring Phenotype Public health Risk factors Science Studies
ISSN:	0028-0836, 1476-4687, 1476-4687
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Buďte první, kdo okomentuje tento záznam!