Modeling Edar expression reveals the hidden dynamics of tooth signaling center patterning

When patterns are set during embryogenesis, it is expected that they are straightly established rather than subsequently modified. The patterning of the three mouse molars is, however, far from straight, likely as a result of mouse evolutionary history. The first-formed tooth signaling centers, call...

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Bibliographic Details
Published in:	PLoS biology Vol. 17; no. 2; p. e3000064
Main Authors:	Sadier, Alexa, Twarogowska, Monika, Steklikova, Klara, Hayden, Luke, Lambert, Anne, Schneider, Pascal, Laudet, Vincent, Hovorakova, Maria, Calvez, Vincent, Pantalacci, Sophie
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 07.02.2019 Public Library of Science (PLoS)
Subjects:	Activation Animals Bernard, Claude (1813-1878) Biochemistry, Molecular Biology Biology and Life Sciences Body Patterning Cell aggregation Chemotaxis Development Biology Developmental biology Edar Receptor - genetics Edar Receptor - metabolism Embryogenesis Embryology and Organogenesis Embryonic growth stage Epithelium - embryology Epithelium - metabolism Funding Gene expression Gene Expression Regulation, Developmental Genetic aspects Genomics Hair Hair - embryology Insects Life Sciences Medicine and Health Sciences Mice Mice, Mutant Strains Models, Biological Molars Morphogenesis Observations Pattern formation Patterning Premolars Signal Transduction Signaling Supervision Teeth Tooth - embryology Tooth - metabolism Tooth Germ - embryology Tooth Germ - metabolism Los Angeles California Czech Republic California France United States > US Jaw Teeth Signaling centers Molars Epithelium Embryos Chemotaxis Embryonic pattern formation
ISSN:	1545-7885, 1544-9173, 1545-7885
Online Access:	Get full text
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