MED12 Alterations in Both Human Benign and Malignant Uterine Soft Tissue Tumors

The relationship between benign uterine leiomyomas and their malignant counterparts, i.e. leiomyosarcomas and smooth muscle tumors of uncertain malignant potential (STUMP), is still poorly understood. The idea that a leiomyosarcoma could derive from a leiomyoma is still controversial. Recently MED12...

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Veröffentlicht in:	PloS one Jg. 7; H. 6; S. e40015
Hauptverfasser:	Pérot, Gaëlle, Croce, Sabrina, Ribeiro, Agnès, Lagarde, Pauline, Velasco, Valérie, Neuville, Agnès, Coindre, Jean-Michel, Stoeckle, Eberhard, Floquet, Anne, MacGrogan, Gaëtan, Chibon, Frédéric
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 29.06.2012 Public Library of Science (PLoS)
Schlagworte:	Alleles Alterations Base Sequence Benign beta Catenin - metabolism Biology Breast cancer Cancer Cell Transformation, Neoplastic - genetics Cell Transformation, Neoplastic - pathology Deoxyribonucleic acid Development and progression DNA DNA Mutational Analysis DNA, Complementary - genetics Female Fibroids Gene expression Gene Expression Regulation, Neoplastic Gene mutation Genetics Genome, Human - genetics Hot spots Humans Immunohistochemistry Leiomyoma - genetics Leiomyoma - pathology Life Sciences Localization Mediator Complex - genetics Mediator Complex - metabolism Medicine Mesenchyme MicroRNAs Molecular Sequence Data Muscles Muscular system Mutation Mutation - genetics Mutation hot spots Pancreatic cancer Pathology Protein Transport RNA polymerase Sequences Smooth muscle Smooth Muscle Tumor - genetics Smooth Muscle Tumor - pathology Soft Tissue Neoplasms - genetics Soft Tissue Neoplasms - pathology Subgroups Tumorigenesis Tumors Uterine cancer Uterine Neoplasms - genetics Uterine Neoplasms - pathology Uterus Wnt protein Wnt Signaling Pathway - genetics β-Catenin France
ISSN:	1932-6203, 1932-6203
Online-Zugang:	Volltext
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