The Evolution of Host Specialization in the Vertebrate Gut Symbiont Lactobacillus reuteri

Recent research has provided mechanistic insight into the important contributions of the gut microbiota to vertebrate biology, but questions remain about the evolutionary processes that have shaped this symbiosis. In the present study, we showed in experiments with gnotobiotic mice that the evolutio...

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Bibliographic Details
Published in:	PLoS genetics Vol. 7; no. 2; p. e1001314
Main Authors:	Frese, Steven A., Benson, Andrew K., Tannock, Gerald W., Loach, Diane M., Kim, Jaehyoung, Zhang, Min, Oh, Phaik Lyn, Heng, Nicholas C. K., Patil, Prabhu B., Juge, Nathalie, MacKenzie, Donald A., Pearson, Bruce M., Lapidus, Alla, Dalin, Eileen, Tice, Hope, Goltsman, Eugene, Land, Miriam, Hauser, Loren, Ivanova, Natalia, Kyrpides, Nikos C., Walter, Jens
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 01.02.2011 Public Library of Science (PLoS)
Subjects:	Animals BASIC BIOLOGICAL SCIENCES BIOLOGY Colleges & universities Comparative analysis Evolution Evolution, Molecular Evolutionary Biology/Evolutionary Ecology Evolutionary Biology/Genomics Evolutionary Biology/Microbial Evolution and Genomics Experiments GASTROINTESTINAL TRACT Gastrointestinal Tract - microbiology GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE GENES Genetic aspects Genetic Fitness Genetics and Genomics/Comparative Genomics Genetics and Genomics/Gene Function Genetics and Genomics/Microbial Evolution and Genomics Genome, Bacterial - genetics Genomes Genomics Host Specificity - genetics Host-bacteria relationships Humans INACTIVATION LACTOBACILLUS Limosilactobacillus reuteri - genetics MICE Microbiology Microbiology/Microbial Evolution and Genomics Microbiota (Symbiotic organisms) Natural history PLASTICITY Polymerase Chain Reaction Proteins Reproducibility of Results Rodentia - microbiology RODENTS Specialization Species Specificity SPECIFICITY STRAINS SYMBIOSIS Symbiosis - genetics VERTEBRATES Vertebrates - microbiology
ISSN:	1553-7404, 1553-7390, 1553-7404
Online Access:	Get full text
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