DNA methylation and body-mass index: a genome-wide analysis

Obesity is a major health problem that is determined by interactions between lifestyle and environmental and genetic factors. Although associations between several genetic variants and body-mass index (BMI) have been identified, little is known about epigenetic changes related to BMI. We undertook a...

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Veröffentlicht in:	The Lancet (British edition) Jg. 383; H. 9933; S. 1990 - 1998
Hauptverfasser:	Dick, Katherine J, Nelson, Christopher P, Tsaprouni, Loukia, Sandling, Johanna K, Aïssi, Dylan, Wahl, Simone, Meduri, Eshwar, Morange, Pierre-Emmanuel, Gagnon, France, Grallert, Harald, Waldenberger, Melanie, Peters, Annette, Erdmann, Jeanette, Hengstenberg, Christian, Cambien, Francois, Goodall, Alison H, Ouwehand, Willem H, Schunkert, Heribert, Thompson, John R, Spector, Tim D, Gieger, Christian, Trégouët, David-Alexandre, Deloukas, Panos, Samani, Nilesh J
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Kidlington Elsevier Ltd 07.06.2014 Elsevier Elsevier Limited
Schlagworte:	Adipose tissue Apoptosis Regulatory Proteins Basic Helix-Loop-Helix Transcription Factors - genetics Biological and medical sciences Body Mass Index Chromosomes, Human, Pair 15 - genetics Chromosomes, Human, Pair 19 - genetics Deoxyribonucleic acid DNA DNA methylation DNA Methylation - genetics Epigenetics Female Gene expression General aspects Genetic factors Genetic variance Genome-Wide Association Study Genomes Humans Hypoxia Internal Medicine Male Medical research Medical sciences Middle Aged Obesity Obesity - genetics Polymorphism, Single Nucleotide - genetics Probes Quality control Repressor Proteins Medicine Body mass index Genome Methylation DNA
ISSN:	0140-6736, 1474-547X, 1474-547X
Online-Zugang:	Volltext
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