Clinical and Virological Factors Influencing the Performance of a NS1 Antigen-Capture Assay and Potential Use as a Marker of Dengue Disease Severity

Detection of dengue NS1 antigen in acute infection has been proposed for early diagnosis of dengue disease. The aim of this study was to evaluate the clinical and virological factors influencing the performance of the Platelia NS1 Ag kit (BioRad) and to assess the potential use of NS1 antigen and de...

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Bibliographic Details
Published in:	PLoS neglected tropical diseases Vol. 5; no. 7; p. e1244
Main Authors:	Duong, Veasna, Ly, Sowath, Lorn Try, Patrich, Tuiskunen, Anne, Ong, Sivuth, Chroeung, Norith, Lundkvist, Ake, Leparc-Goffart, Isabelle, Deubel, Vincent, Vong, Sirenda, Buchy, Philippe
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 01.07.2011 Public Library of Science (PLoS)
Subjects:	Antibodies, Viral - blood Antibodies, Viral - immunology Antigens Antigens, Viral - analysis Antigens, Viral - immunology Biology Biomarkers - analysis Care and treatment Child Child, Preschool Dengue Dengue - diagnosis Dengue - immunology Dengue - virology Dengue Virus - genetics Dengue Virus - immunology Dengue Virus - isolation & purification Diagnosis Disease Progression Enzyme-linked immunosorbent assay Enzyme-Linked Immunosorbent Assay - methods Female Health aspects Humans Immunoglobulin M - blood Life Sciences Logistic Models Male Medicine Microbiology and Parasitology Multivariate Analysis Reagent Kits, Diagnostic RNA, Viral - analysis Viral Load Viral Nonstructural Proteins - analysis Viral Nonstructural Proteins - immunology Virology Cambodia France Sweden Immunoglobulin M Multivariate Analysis Antigens Viral Nonstructural Proteins RNA Enzyme-Linked Immunosorbent Assay Biological Markers Humans Dengue Viral Preschool Antibodies Logistic Models Male Diagnostic Viral Load Disease Progression Dengue Virus Reagent Kits Female Child Child, Preschool Antibodies, Viral Antigens, Viral RNA, Viral Reagent Kits, Diagnostic
ISSN:	1935-2735, 1935-2727, 1935-2735
Online Access:	Get full text
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