The effect of some family characteristics on the relationship between mental symptoms and levels of serum serotonin and salivatory cortisol

Aim: Psychological symptoms (PSs) are also seen in healthy individuals. The aim of this study is to examine some familial features in the relationship between PSs and serum serotonin (5-HT) and salivary cortisol (CTS) levels in healthy subjects. Materials and Method: Sociodemographic data form and p...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Journal of health sciences and medicine : (Turkey) Ročník 6; číslo 1; s. 165 - 173
Hlavní autoři: MADEN, Özgür, UZUN, Özcan
Médium: Journal Article
Jazyk:angličtina
Vydáno: 12.01.2023
ISSN:2636-8579, 2636-8579
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Abstract Aim: Psychological symptoms (PSs) are also seen in healthy individuals. The aim of this study is to examine some familial features in the relationship between PSs and serum serotonin (5-HT) and salivary cortisol (CTS) levels in healthy subjects. Materials and Method: Sociodemographic data form and psychiatric symptom screening questionnaire (SCL-90-R) were given to 320 healthy individuals (156 males, 164 females) aged 18-65 without any mental illness. Blood and saliva samples were duly taken and evaluated by ELISA method. Informed consent and local ethics committee approval were obtained from the participants before starting the study. Statistical analyzes were done with SPSS 15.0 program. Descriptive statistical data (number, percentage, mean, standard deviation, minimum and maximum), independent sample t-test, One-way ANOVA test, Pearson Correlation analysis were used in the analyzes. For statistical significance, p<.05 was accetted significant.Results: The mean age of the participants was 29.19±8.41. According to family characteristics, PSs were found to be higher in those whose parents were separated, whose parents had a low educational level, and those with a family history of psychiatric illness. Depressive symptoms were statistically significantly higher in those whose families were separated. Somatization, anxiety, obsessive symptoms, depressive symptoms, hostility and additional symptoms were statistically significantly higher in those with a family history of psychiatric illness. Although it was not statistically significant, the 5-HT levels were highest in those living in an extended family, those whose parents lived together, those whose parents were primary school graduates, and those who did not have a family history of psychiatric disease. CTS levels were statistically significantly higher in those who did not have a family history of psychiatric disease. There was a negative correlation between 5-HT and CTS levels and PSs excluding additional symptoms. There was a positive correlation between 5-HT and CTS levels.Conclusion: It was concluded that familial characteristics have an effect on the relationship between psychological symptoms and serotonin and cortisol levels in healthy individuals, but these characteristics alone are not effective in this relationship. There is a need for studies investigating other stressor factors that are thought to be effective in the relationship between mental symptoms and serotonin and cortisol levels.
AbstractList Aim: Psychological symptoms (PSs) are also seen in healthy individuals. The aim of this study is to examine some familial features in the relationship between PSs and serum serotonin (5-HT) and salivary cortisol (CTS) levels in healthy subjects. Materials and Method: Sociodemographic data form and psychiatric symptom screening questionnaire (SCL-90-R) were given to 320 healthy individuals (156 males, 164 females) aged 18-65 without any mental illness. Blood and saliva samples were duly taken and evaluated by ELISA method. Informed consent and local ethics committee approval were obtained from the participants before starting the study. Statistical analyzes were done with SPSS 15.0 program. Descriptive statistical data (number, percentage, mean, standard deviation, minimum and maximum), independent sample t-test, One-way ANOVA test, Pearson Correlation analysis were used in the analyzes. For statistical significance, p<.05 was accetted significant.Results: The mean age of the participants was 29.19±8.41. According to family characteristics, PSs were found to be higher in those whose parents were separated, whose parents had a low educational level, and those with a family history of psychiatric illness. Depressive symptoms were statistically significantly higher in those whose families were separated. Somatization, anxiety, obsessive symptoms, depressive symptoms, hostility and additional symptoms were statistically significantly higher in those with a family history of psychiatric illness. Although it was not statistically significant, the 5-HT levels were highest in those living in an extended family, those whose parents lived together, those whose parents were primary school graduates, and those who did not have a family history of psychiatric disease. CTS levels were statistically significantly higher in those who did not have a family history of psychiatric disease. There was a negative correlation between 5-HT and CTS levels and PSs excluding additional symptoms. There was a positive correlation between 5-HT and CTS levels.Conclusion: It was concluded that familial characteristics have an effect on the relationship between psychological symptoms and serotonin and cortisol levels in healthy individuals, but these characteristics alone are not effective in this relationship. There is a need for studies investigating other stressor factors that are thought to be effective in the relationship between mental symptoms and serotonin and cortisol levels.
Author MADEN, Özgür
UZUN, Özcan
Author_xml – sequence: 1
  givenname: Özgür
  orcidid: 0000-0002-0430-5747
  surname: MADEN
  fullname: MADEN, Özgür
– sequence: 2
  givenname: Özcan
  orcidid: 0000-0002-4244-6911
  surname: UZUN
  fullname: UZUN, Özcan
BookMark eNpNkElqAzEQRUVwII7jZfa6QDsaelwGkwkM2XjflNUlWkaDkRQHnyGXjt3xIpuqgv95Be-ezHzwSMgjZysppBBP-zG5FeetEKy8IXNRy7poq6ab_bvvyDKlPWNMVKyqWjknP9sRKWqNKtOgaQoOqQZn7ImqESKojNGkbFSiwdN8Lke0kE3waTQHusP8jeipQ5_B0nRyhxxcouAHavGINk1UjF_uMkMO3vgpTWDNEXKI50chZpOCfSC3GmzC5XUvyPb1Zbt-Lzafbx_r502hmqYsgCPfCaw7pbmSlRqA71pWYQmMl1yCbMQAbSU73Ure1ZpLNaiubIGXahiaQS5I8YdVMaQUUfeHaBzEU89ZP7nsLy77q0v5CziIbcU
Cites_doi 10.1192/bjp.180.2.99
10.1007/s00127-013-0697-8
10.1016/j.jad.2017.04.015
10.1007/978-981-32-9705-0_9
10.1002/ajmg.b.32766
10.1016/j.psychres.2004.04.010
10.1016/j.psychres.2004.04.001
10.1111/pcn.12944
10.1111/j.1440-1819.2011.02252.x
10.1186/s13587-014-0015-4
10.1002/1097-4679(197710)33:4<981::AID-JCLP2270330412>3.0.CO;2-0
10.1016/0165-1781(93)90003-Y
10.1016/j.psychres.2020.113166
10.1001/archgenpsychiatry.2009.50
10.1371/journal.pone.0114526
10.3389/fncel.2017.00139
10.3390/jcm10215204
10.1111/cch.12342
10.3389/fnbeh.2018.00127
10.1016/j.neubiorev.2021.12.018
10.1037/a0018399
10.1017/S0033291706009184
10.1001/jamapsychiatry.2015.0071
10.4103/jnrp.jnrp_425_16
10.1530/JOE-19-0546
10.1111/ejn.15205
10.1080/13651501.2017.1411516
10.1016/j.comppsych.2013.08.002
10.1097/01.PSY.0000073872.85623.0C
10.1007/s10571-021-01064-9
10.1016/j.psyneuen.2018.09.020
10.1001/archpsyc.1992.01820060022003
10.1016/j.psyneuen.2008.07.004
10.1038/s41398-018-0128-4
10.1038/mp.2016.68
10.1002/jclp.20497
10.1111/jomf.12637
10.1007/978-3-7091-9113-2_21
ContentType Journal Article
DBID AAYXX
CITATION
DOI 10.32322/jhsm.1182204
DatabaseName CrossRef
DatabaseTitle CrossRef
DatabaseTitleList CrossRef
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 2636-8579
EndPage 173
ExternalDocumentID 10_32322_jhsm_1182204
GroupedDBID AAYXX
ALMA_UNASSIGNED_HOLDINGS
CITATION
GROUPED_DOAJ
M~E
OK1
ID FETCH-LOGICAL-c774-a1e1b2e69cf1c35cda1b805e4a01413a372da8539f83196f13cdc948a14cdd7d3
ISSN 2636-8579
IngestDate Sat Nov 29 02:11:29 EST 2025
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 1
Language English
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c774-a1e1b2e69cf1c35cda1b805e4a01413a372da8539f83196f13cdc948a14cdd7d3
ORCID 0000-0002-0430-5747
0000-0002-4244-6911
OpenAccessLink https://dergipark.org.tr/en/download/article-file/2679941
PageCount 9
ParticipantIDs crossref_primary_10_32322_jhsm_1182204
PublicationCentury 2000
PublicationDate 2023-01-12
PublicationDateYYYYMMDD 2023-01-12
PublicationDate_xml – month: 01
  year: 2023
  text: 2023-01-12
  day: 12
PublicationDecade 2020
PublicationTitle Journal of health sciences and medicine : (Turkey)
PublicationYear 2023
References ref13
ref35
ref12
ref34
ref15
ref37
ref14
ref36
ref31
ref30
ref11
ref33
ref10
ref32
ref2
ref1
ref17
ref39
ref16
ref38
ref19
ref18
ref24
ref23
ref26
ref25
ref20
ref42
ref41
ref22
ref21
ref28
ref27
ref29
ref8
ref7
ref9
ref4
ref3
ref6
ref5
ref40
References_xml – ident: ref40
  doi: 10.1192/bjp.180.2.99
– ident: ref16
  doi: 10.1007/s00127-013-0697-8
– ident: ref24
  doi: 10.1016/j.jad.2017.04.015
– ident: ref7
  doi: 10.1007/978-981-32-9705-0_9
– ident: ref22
– ident: ref5
  doi: 10.1002/ajmg.b.32766
– ident: ref9
  doi: 10.1016/j.psychres.2004.04.010
– ident: ref32
  doi: 10.1016/j.psychres.2004.04.001
– ident: ref34
  doi: 10.1111/pcn.12944
– ident: ref20
  doi: 10.1111/j.1440-1819.2011.02252.x
– ident: ref13
– ident: ref27
  doi: 10.1186/s13587-014-0015-4
– ident: ref21
  doi: 10.1002/1097-4679(197710)33:4<981::AID-JCLP2270330412>3.0.CO;2-0
– ident: ref36
  doi: 10.1016/0165-1781(93)90003-Y
– ident: ref29
  doi: 10.1016/j.psychres.2020.113166
– ident: ref10
  doi: 10.1001/archgenpsychiatry.2009.50
– ident: ref17
  doi: 10.1371/journal.pone.0114526
– ident: ref2
  doi: 10.3389/fncel.2017.00139
– ident: ref12
  doi: 10.3390/jcm10215204
– ident: ref28
  doi: 10.1111/cch.12342
– ident: ref39
  doi: 10.3389/fnbeh.2018.00127
– ident: ref31
  doi: 10.1016/j.neubiorev.2021.12.018
– ident: ref8
  doi: 10.1037/a0018399
– ident: ref19
  doi: 10.1017/S0033291706009184
– ident: ref26
  doi: 10.1001/jamapsychiatry.2015.0071
– ident: ref23
– ident: ref37
  doi: 10.4103/jnrp.jnrp_425_16
– ident: ref1
  doi: 10.1530/JOE-19-0546
– ident: ref3
  doi: 10.1111/ejn.15205
– ident: ref33
  doi: 10.1080/13651501.2017.1411516
– ident: ref30
  doi: 10.1016/j.comppsych.2013.08.002
– ident: ref11
  doi: 10.1097/01.PSY.0000073872.85623.0C
– ident: ref6
  doi: 10.1007/s10571-021-01064-9
– ident: ref35
  doi: 10.1016/j.psyneuen.2018.09.020
– ident: ref41
  doi: 10.1001/archpsyc.1992.01820060022003
– ident: ref38
  doi: 10.1016/j.psyneuen.2008.07.004
– ident: ref4
  doi: 10.1038/s41398-018-0128-4
– ident: ref25
  doi: 10.1038/mp.2016.68
– ident: ref18
  doi: 10.1002/jclp.20497
– ident: ref15
  doi: 10.1111/jomf.12637
– ident: ref42
  doi: 10.1007/978-3-7091-9113-2_21
– ident: ref14
SSID ssj0002505583
Score 2.2063813
Snippet Aim: Psychological symptoms (PSs) are also seen in healthy individuals. The aim of this study is to examine some familial features in the relationship between...
SourceID crossref
SourceType Index Database
StartPage 165
Title The effect of some family characteristics on the relationship between mental symptoms and levels of serum serotonin and salivatory cortisol
Volume 6
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVAON
  databaseName: DOAJ Directory of Open Access Journals
  customDbUrl:
  eissn: 2636-8579
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0002505583
  issn: 2636-8579
  databaseCode: DOA
  dateStart: 20180101
  isFulltext: true
  titleUrlDefault: https://www.doaj.org/
  providerName: Directory of Open Access Journals
– providerCode: PRVHPJ
  databaseName: ROAD: Directory of Open Access Scholarly Resources (ISSN International Center)
  customDbUrl:
  eissn: 2636-8579
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0002505583
  issn: 2636-8579
  databaseCode: M~E
  dateStart: 20180101
  isFulltext: true
  titleUrlDefault: https://road.issn.org
  providerName: ISSN International Centre
link http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtZ1Lj9MwEICtsiDEBfEUz5UPiAvKUifOw0dYgbh0xaErrbhUtmPz2Capmna1cOAP8Lf4YczYThrCIi0HLmllN6O48ykej8czhDwrEzNVmeCR4jKNuLUykoKryPJUp5mdMqWsKzaRHx0VJyfi_WTyszsLc7bM67o4Pxer_6pqaANl49HZf1B3LxQa4DsoHa6gdrheWvE-SgMNwbapTOfF0KPkzH6fIBxnGcVthZz_7ddqtWkqn8h5iQFGLvQDBrKt8Nps0J3reluJu0puzx5WtJvPbbP8i-Xrz16-CJOvl93t8TsXBVi98-36FL3pvZ9iBsi4kATc2hfZt4_4-fqwjy0-_nA87NaB-uDQiDGcK2IDH2ecYY7k1NeYOTAXtIUXd_YHn_4lzHz1iTCfM18qZTxVJGBKYu7ZL5_a6gBXWbEvg_x7Su7RVNkHMMLSyQlY4O2LcPsVcjXOU4GBhbPvO08fGpmpywfbj8Ine3USXg4fYGAcDayc-S1yMyiJvvJY3SYTU98h12dBOXfJD6CLerpoYynSRT1ddEQXbWoKdNEhXTTQRT1dtKOLAgHU0-WkIl20p8v17uiiHV33yPztm_nhuyjU84g0LDIiyQxTscmEtkwnqS4lU8U0NVxisHEikzwuJViPwhY4L1iW6FILXkjGdVnmZXKf7NVNbR4QyqzVKjdJrKTkXINIJdRUihwXDIqLh-R59z8uVj5ry-JClT267A8fkxs7Vp-Qvc16a56Sa_oMBrzed56cfaf2X0INlPo
linkProvider ISSN International Centre
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+effect+of+some+family+characteristics+on+the+relationship+between+mental+symptoms+and+levels+of+serum+serotonin+and+salivatory+cortisol&rft.jtitle=Journal+of+health+sciences+and+medicine+%3A+%28Turkey%29&rft.au=MADEN%2C+%C3%96zg%C3%BCr&rft.au=UZUN%2C+%C3%96zcan&rft.date=2023-01-12&rft.issn=2636-8579&rft.eissn=2636-8579&rft.volume=6&rft.issue=1&rft.spage=165&rft.epage=173&rft_id=info:doi/10.32322%2Fjhsm.1182204&rft.externalDBID=n%2Fa&rft.externalDocID=10_32322_jhsm_1182204
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2636-8579&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2636-8579&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2636-8579&client=summon