Identifying the Common Genetic Basis of Antidepressant Response

Antidepressants are a first-line treatment for depression. However, only a third of individuals experience remission after the first treatment. Common genetic variation, in part, likely regulates antidepressant response, yet the success of previous genome-wide association studies has been limited by...

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Published in:	Biological Psychiatry Global Open Science Vol. 2; no. 2; pp. 115 - 126
Main Authors:	Pain, Oliver, Adams, Mark J., Byrne, Enda M., Cattaneo, Annamaria, Als, Thomas D., Hayward, Caroline, Henigsberg, Neven, Lewis, Glyn, Martin, Nicholas G., Mors, Ole, Rentería, Miguel E., Reynolds, Charles F., Rietschel, Marcella, Uher, Rudolf, Wigmore, Eleanor M., Baune, Bernhard T., Domschke, Katharina, Li, Qingqin S., Serretti, Alessandro, Turecki, Gustavo, Weinshilboum, Richard, Montgomery, Stuart, Mendlewicz, Julien, Wray, Naomi R., Ripke, Stephan, Trzaskowski, Maciej, Abdellaoui, Abdel, Agerbo, Esben, Andlauer, Till F.M., Bybjerg-Grauholm, Jonas, Clarke, Toni-Kim, Deary, Ian J., Derks, Eske M., Direk, Nese, Dolan, Conor V., Dunn, Erin C., Escott-Price, Valentina, Hassan Kiadeh, Farnush Farhadi, Gordon, Scott D., Hickie, Ian B., Horn, Carsten, Hottenga, Jouke-Jan, Howard, David M., Ising, Marcus, Jansen, Rick, Jones, Lisa A., Jorgenson, Eric, Kraft, Julia, Kretzschmar, Warren W., Maier, Wolfgang, Marchini, Jonathan, McGrath, Patrick, Mehta, Divya, Mondimore, Francis M., Mostafavi, Sara, Mullins, Niamh, Nyholt, Dale R., O’Reilly, Paul F., Oskarsson, Hogni, Owen, Michael J., Pedersen, Carsten Bøcker, Pedersen, Marianne Giørtz, Peyrot, Wouter J., Pistis, Giorgio, Mirza, Saira Saeed, Schoevers, Robert, Shi, Jianxin, Sigurdsson, Engilbert, Steinberg, Stacy, Streit, Fabian, Strohmaier, Jana, Teumer, Alexander, Thompson, Wesley, Thorgeirsson, Thorgeir E., Treutlein, Jens, Trubetskoy, Vassily, Van der Auwera, Sandra, van Hemert, Albert M., Visscher, Peter M., Wang, Yunpeng, Webb, Bradley T., Weinsheimer, Shantel Marie, Zhang, Futao, Berger, Klaus, Boomsma, Dorret I., Domenici, Enrico, Grabe, Hans J., Kloiber, Stefan, Magnusson, Patrik K., Mortensen, Preben Bo, Paciga, Sara A., Porteous, David J., Stefansson, Kari, Werge, Thomas, Lewis, Cathryn M., Levinson, Douglas F.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.04.2022 Elsevier BV Elsevier Inc. on behalf of Society of Biological Psychiatry Elsevier
Subjects:	Antidepressant response Antidepressant response ; Depression ; Genetics ; GWAS ; MDD ; Polygenic score Antidepressant response; Depression; GWAS; Genetics; MDD; Polygenic score Archival Report Depression Genetics GWAS info:eu-repo/classification/ddc/610 info:eu-repo/classification/ddc/616.89 MDD Polygenic score Psychiatric/Mental Health Psychiatry RC435-571 SDG 3 - Good Health and Well-being Polygenic score Depression Genetics GWAS MDD Antidepressant response
ISSN:	2667-1743, 2667-1743
Online Access:	Get full text
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