DNA methylation aging clocks: challenges and recommendations

Epigenetic clocks comprise a set of CpG sites whose DNA methylation levels measure subject age. These clocks are acknowledged as a highly accurate molecular correlate of chronological age in humans and other vertebrates. Also, extensive research is aimed at their potential to quantify biological agi...

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Bibliographic Details
Published in:	Genome Biology Vol. 20; no. 1; p. 249
Main Authors:	Bell, Christopher G., Lowe, Robert, Adams, Peter D., Baccarelli, Andrea A., Beck, Stephan, Bell, Jordana T., Christensen, Brock C., Gladyshev, Vadim N., Heijmans, Bastiaan T., Horvath, Steve, Ideker, Trey, Issa, Jean-Pierre J., Kelsey, Karl T., Marioni, Riccardo E., Reik, Wolf, Relton, Caroline L., Schalkwyk, Leonard C., Teschendorff, Andrew E., Wagner, Wolfgang, Zhang, Kang, Rakyan, Vardhman K.
Format:	Journal Article
Language:	English
Published:	London BioMed Central 25.11.2019 Springer Nature B.V BMC
Subjects:	Age Age determination Aging Aging - metabolism Animal Genetics and Genomics Animals Bioinformatics Biological Clocks biomarkers Biomedical and Life Sciences Cell culture CpG islands Deoxyribonucleic acid DNA DNA Methylation Epigenesis, Genetic epigenetics epigenome ethics Evolutionary Biology Forensic science forensic sciences Genome, Human Genome-Wide Association Study Human Genetics Humans Life Sciences longevity Microbial Genetics and Genomics Plant Genetics and Genomics Population studies Review
ISSN:	1474-760X, 1474-7596, 1474-760X
Online Access:	Get full text
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