Detection of breast cancer lymph node metastases in frozen sections with a point-of-care low-cost microscope scanner

Detection of lymph node metastases is essential in breast cancer diagnostics and staging, affecting treatment and prognosis. Intraoperative microscopy analysis of sentinel lymph node frozen sections is standard for detection of axillary metastases but requires access to a pathologist for sample anal...

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Bibliographic Details
Published in:	PloS one Vol. 14; no. 3; p. e0208366
Main Authors:	Holmström, Oscar, Linder, Nina, Moilanen, Hannu, Suutala, Antti, Nordling, Stig, Ståhls, Anders, Lundin, Mikael, Diwan, Vinod, Lundin, Johan
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 19.03.2019 Public Library of Science (PLoS)
Subjects:	Biology and Life Sciences Biopsy Breast cancer Breast Neoplasms - pathology Cancer Cancer diagnosis Cancer metastasis Cancer patients Cancer surgery Care and treatment Cost analysis Diagnosis Digital imaging Digitization Engineering and Technology Female Frozen Sections Frozen sections (Histology) Ground truth Health sciences Histopathology Hospitals Humans Image acquisition Image detection Image quality Laboratories Light microscopy Low cost Lymph node biopsy Lymph nodes Lymph Nodes - pathology Lymphatic Metastasis - diagnostic imaging Lymphatic Metastasis - pathology Lymphatic system Maternal & child health Medical diagnosis Medical imaging Medical prognosis Medicine Medicine and Health Sciences Metastases Metastasis Methods Microscopy Microscopy - economics Microscopy - instrumentation Miniaturization Onsite Pathology Point-of-Care Systems - economics Prognosis Public health Research and Analysis Methods Retrospective Studies Scanners Sensitivity and Specificity Smartphones Studies Surgery Womens health Workflow Workflow software Sweden Finland
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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