Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

Genetic association studies, in particular the genome-wide association study (GWAS) design, have provided a wealth of novel insights into the aetiology of a wide range of human diseases and traits, in particular cardiovascular diseases and lipid biomarkers. The next challenge consists of understandi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS genetics Jg. 10; H. 5; S. e1004383
Hauptverfasser:	Giambartolomei, Claudia, Vukcevic, Damjan, Schadt, Eric E., Franke, Lude, Hingorani, Aroon D., Wallace, Chris, Plagnol, Vincent
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 01.05.2014 Public Library of Science (PLoS)
Schlagworte:	Bayes Theorem Bayesian statistical decision theory Biology and Life Sciences Biomarkers Biomedical research Computer and Information Sciences Disease Gene expression Gene loci Genome-wide association studies Genome-Wide Association Study Genomes Humans Lipids Medical research Medicine and Health Sciences Meta-analysis Methods Probability Sample Size Statistical analysis Statistical methods Statistics Studies
ISSN:	1553-7404, 1553-7390, 1553-7404
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!