Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

Genetic association studies, in particular the genome-wide association study (GWAS) design, have provided a wealth of novel insights into the aetiology of a wide range of human diseases and traits, in particular cardiovascular diseases and lipid biomarkers. The next challenge consists of understandi...

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Vydáno v:	PLoS genetics Ročník 10; číslo 5; s. e1004383
Hlavní autoři:	Giambartolomei, Claudia, Vukcevic, Damjan, Schadt, Eric E., Franke, Lude, Hingorani, Aroon D., Wallace, Chris, Plagnol, Vincent
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Public Library of Science 01.05.2014 Public Library of Science (PLoS)
Témata:	Bayes Theorem Bayesian statistical decision theory Biology and Life Sciences Biomarkers Biomedical research Computer and Information Sciences Disease Gene expression Gene loci Genome-wide association studies Genome-Wide Association Study Genomes Humans Lipids Medical research Medicine and Health Sciences Meta-analysis Methods Probability Sample Size Statistical analysis Statistical methods Statistics Studies
ISSN:	1553-7404, 1553-7390, 1553-7404
On-line přístup:	Získat plný text
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