Multidrug Resistant Pulmonary Tuberculosis Treatment Regimens and Patient Outcomes: An Individual Patient Data Meta-analysis of 9,153 Patients

Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic, expensive, and has generally poor outcomes. We undertook an individual patient data meta-analysis to assess the impact on outcomes of the type, number, and duration of drugs used to treat MDR-TB. Three recent systematic review...

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Veröffentlicht in:	PLoS medicine Jg. 9; H. 8; S. e1001300
Hauptverfasser:	Ahuja, Shama D., Ashkin, David, Avendano, Monika, Banerjee, Rita, Bauer, Melissa, Bayona, Jamie N., Becerra, Mercedes C., Benedetti, Andrea, Burgos, Marcos, Centis, Rosella, Chan, Eward D., Chiang, Chen-Yuan, Cox, Helen, D'Ambrosio, Lia, DeRiemer, Kathy, Dung, Nguyen Huy, Enarson, Donald, Falzon, Dennis, Flanagan, Katherine, Flood, Jennifer, Garcia-Garcia, Maria L., Gandhi, Neel, Granich, Reuben M., Hollm-Delgado, Maria G., Holtz, Timothy H., Iseman, Michael D., Jarlsberg, Leah G., Keshavjee, Salmaan, Kim, Hye-Ryoun, Koh, Won-Jung, Lancaster, Joey, Lange, Christophe, de Lange, Wiel C. M., Leimane, Vaira, Leung, Chi Chiu, Li, Jiehui, Menzies, Dick, Migliori, Giovanni B., Mishustin, Sergey P., Mitnick, Carole D., Narita, Masa, O'Riordan, Philly, Pai, Madhukar, Palmero, Domingo, Park, Seung-kyu, Pasvol, Geoffrey, Peña, Jose, Pérez-Guzmán, Carlos, Quelapio, Maria I. D., Ponce-de-Leon, Alfredo, Riekstina, Vija, Robert, Jerome, Royce, Sarah, Schaaf, H. Simon, Seung, Kwonjune J., Shah, Lena, Shim, Tae Sun, Shin, Sonya S., Shiraishi, Yuji, Sifuentes-Osornio, José, Sotgiu, Giovanni, Strand, Matthew J., Tabarsi, Payam, Tupasi, Thelma E., van Altena, Robert, Van der Walt, Martie, Van der Werf, Tjip S., Vargas, Mario H., Viiklepp, Pirett, Westenhouse, Janice, Yew, Wing Wai, Yim, Jae-Joon
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 01.08.2012 Public Library of Science (PLoS)
Schlagworte:	Adult Antitubercular Agents - therapeutic use Clinical trials Confidence Intervals Drug resistance Drug therapy Female Health aspects Humans Male Medicine Meta-analysis Odds Ratio Patient outcomes Physiological aspects Pulmonary tuberculosis Recurrence Studies Treatment Failure Tuberculosis Tuberculosis, Multidrug-Resistant - drug therapy United States South Korea Philippines Recurrence Confidence Intervals Tuberculosis, Multidrug-Resistant Antitubercular Agents Humans Treatment Failure Adult Female Male Odds Ratio
ISSN:	1549-1676, 1549-1277, 1549-1676
Online-Zugang:	Volltext
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