Estimated stroke risk, yield, and number needed to screen for atrial fibrillation detected through single time screening: a multicountry patient-level meta-analysis of 141,220 screened individuals

The precise age distribution and calculated stroke risk of screen-detected atrial fibrillation (AF) is not known. Therefore, it is not possible to determine the number needed to screen (NNS) to identify one treatable new AF case (NNS-Rx) (i.e., Class-1 oral anticoagulation [OAC] treatment recommenda...

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Bibliographic Details
Published in:	PLoS medicine Vol. 16; no. 9; p. e1002903
Main Authors:	Lowres, Nicole, Olivier, Jake, Chao, Tze-Fan, Chen, Shih-Ann, Chen, Yi, Diederichsen, Axel, Fitzmaurice, David A., Gomez-Doblas, Juan Jose, Harbison, Joseph, Healey, Jeff S., Hobbs, F. D. Richard, Kaasenbrood, Femke, Keen, William, Lee, Vivian W., Lindholt, Jes S., Lip, Gregory Y. H., Mairesse, Georges H., Mant, Jonathan, Martin, Julie W., Martín-Rioboó, Enrique, McManus, David D., Muñiz, Javier, Münzel, Thomas, Nakamya, Juliet, Neubeck, Lis, Orchard, Jessica J., Pérula de Torres, Luis Ángel, Proietti, Marco, Quinn, F. Russell, Roalfe, Andrea K., Sandhu, Roopinder K., Schnabel, Renate B., Smyth, Breda, Soni, Apurv, Tieleman, Robert, Wang, Jiguang, Wild, Philipp S., Yan, Bryan P., Freedman, Ben
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 25.09.2019 Public Library of Science (PLoS)
Subjects:	Adult Age composition Age Factors Aged Aged, 80 and over Anticoagulants Atrial fibrillation Atrial Fibrillation - complications Atrial Fibrillation - diagnosis Atrial Fibrillation - physiopathology Biology and Life Sciences Budgets Cardiac arrhythmia Cardiology Clinical medicine Computer simulation Cost analysis Dependence Diagnosis Electrocardiography Female Fibrillation Health risks Health sciences Heart Hospitals Humans International cooperation Male Males Mass Screening - methods Medical economics Medical research Medicine Medicine and Health Sciences Meta-analysis Middle Aged People and Places Poisson density functions Predictive Value of Tests Primary care Prognosis Research and Analysis Methods Risk Assessment Risk Factors Sex Factors Social Sciences Statistical analysis Stroke Stroke - etiology Systematic review Yield Young Adult United Kingdom > UK United States > US New South Wales Australia Spain Ontario Canada Canada Netherlands Ireland China Taiwan Denmark Italy Australia Germany
ISSN:	1549-1676, 1549-1277, 1549-1676
Online Access:	Get full text
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