A General Approach for Haplotype Phasing across the Full Spectrum of Relatedness

Many existing cohorts contain a range of relatedness between genotyped individuals, either by design or by chance. Haplotype estimation in such cohorts is a central step in many downstream analyses. Using genotypes from six cohorts from isolated populations and two cohorts from non-isolated populati...

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Veröffentlicht in:PLoS genetics Jg. 10; H. 4; S. e1004234
Hauptverfasser: O'Connell, Jared, Gurdasani, Deepti, Delaneau, Olivier, Pirastu, Nicola, Ulivi, Sheila, Cocca, Massimiliano, Traglia, Michela, Huang, Jie, Huffman, Jennifer E., Rudan, Igor, McQuillan, Ruth, Fraser, Ross M., Campbell, Harry, Polasek, Ozren, Asiki, Gershim, Ekoru, Kenneth, Hayward, Caroline, Wright, Alan F., Vitart, Veronique, Navarro, Pau, Zagury, Jean-Francois, Wilson, James F., Toniolo, Daniela, Gasparini, Paolo, Soranzo, Nicole, Sandhu, Manjinder S., Marchini, Jonathan
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States Public Library of Science 01.04.2014
Public Library of Science (PLoS)
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ISSN:1553-7404, 1553-7390, 1553-7404
Online-Zugang:Volltext
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