Estimating the impact of antiretroviral treatment on adult mortality trends in South Africa: A mathematical modelling study

Substantial reductions in adult mortality have been observed in South Africa since the mid-2000s, but there has been no formal evaluation of how much of this decline is attributable to the scale-up of antiretroviral treatment (ART), as previous models have not been calibrated to vital registration d...

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Bibliographic Details
Published in:	PLoS medicine Vol. 14; no. 12; p. e1002468
Main Authors:	Johnson, Leigh F., May, Margaret T., Dorrington, Rob E., Cornell, Morna, Boulle, Andrew, Egger, Matthias, Davies, Mary-Ann
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 12.12.2017 Public Library of Science (PLoS)
Subjects:	Acquired immune deficiency syndrome Adult Adults AIDS Antiretroviral agents Antiretroviral drugs Antiretroviral therapy Antiretroviral Therapy, Highly Active - methods Bayes Theorem Bayesian analysis Biology and Life Sciences Computer simulation Death Drug therapy Epidemics Epidemiology Fatalities Female Health care Highly active antiretroviral therapy HIV HIV Infections - drug therapy HIV Infections - mortality HIV Infections - transmission Human immunodeficiency virus Humans Infectious diseases Life expectancy Male Mathematical models Medicine and Health Sciences Middle Aged Models, Theoretical Mortality Mortality - trends Patient outcomes People and places Population Preventive medicine Registration South Africa - epidemiology Studies Trends Tuberculosis Young Adult South Africa
ISSN:	1549-1676, 1549-1277, 1549-1676
Online Access:	Get full text
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