Patterns of Immune Infiltration in Breast Cancer and Their Clinical Implications: A Gene-Expression-Based Retrospective Study

Immune infiltration of breast tumours is associated with clinical outcome. However, past work has not accounted for the diversity of functionally distinct cell types that make up the immune response. The aim of this study was to determine whether differences in the cellular composition of the immune...

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Veröffentlicht in:	PLoS medicine Jg. 13; H. 12; S. e1002194
Hauptverfasser:	Ali, H. Raza, Chlon, Leon, Pharoah, Paul D. P., Markowetz, Florian, Caldas, Carlos
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 13.12.2016 Public Library of Science (PLoS)
Schlagworte:	Biology and Life Sciences Biomedical research Breast cancer Breast Neoplasms - genetics Breast Neoplasms - immunology Cancer therapies Care and treatment Chemotherapy Cluster Analysis Datasets Development and progression Female Gene Expression Genetic aspects Health aspects Humans Immune response Immunotherapy Lymphocytes Medical prognosis Medical research Medicine and Health Sciences Oncogenes Proportional Hazards Models Retrospective Studies Studies T cell receptors Tumors
ISSN:	1549-1676, 1549-1277, 1549-1676
Online-Zugang:	Volltext
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