In Vivo, Non-Invasive Characterization of Human Bone by Hybrid Broadband (600-1200 nm) Diffuse Optical and Correlation Spectroscopies

Non-invasive in vivo diffuse optical characterization of human bone opens a new possibility of diagnosing bone related pathologies. We present an in vivo characterization performed on seventeen healthy subjects at six different superficial bone locations: radius distal, radius proximal, ulna distal,...

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Bibliographic Details
Published in:	PLOS ONE Vol. 11; no. 12; p. e0168426
Main Authors:	Konugolu Venkata Sekar, Sanathana, Pagliazzi, Marco, Negredo, Eugènia, Martelli, Fabrizio, Farina, Andrea, Dalla Mora, Alberto, Lindner, Claus, Farzam, Parisa, Pérez-Álvarez, Núria, Puig, Jordi, Taroni, Paola, Pifferi, Antonio, Durduran, Turgut
Format:	Journal Article Publication
Language:	English
Published:	United States Public Library of Science (PLoS) 20.12.2016 Public Library of Science
Subjects:	90 Operations research, mathematical programming 90 Operations research, mathematical programming [Classificació AMS] Adult Biology and Life Sciences Blood Blood flow bone Bone blood flow Bone density Bones Broadband Calcaneus Classificació AMS Classificació AMS::90 Operations research Classificació AMS::90 Operations research, mathematical programming Collagen Contrast agents Correlation Diagnostic imaging diffuse spectroscopy diffuse-correlation spectroscopy Female Human Bone, Diffuse Correlation Spectroscopy Humans Innovations Investigació operativa Lipids Male Matemàtiques i estadística Matemàtiques i estadística::Investigació operativa [Àrees temàtiques de la UPC] mathematical programming Medical imaging Medicine Medicine and Health Sciences Metabolism Microvasculature Middle Aged NMR Nuclear magnetic resonance Observations Optical properties Osteoporosis Oxygen Oxygen Consumption Oxygen consumption (Metabolism) Oxygen metabolism Patient care Penetration depth Perfusion Physical Sciences Physiology Point-of-Care Systems Q R Radius Radius - diagnostic imaging Radius - metabolism Research and Analysis Methods Research Article Science Spectrophotometry Spectrophotometry - instrumentation Spectrophotometry - methods Spectroscopy Spectrum analysis Technology application TIME-RESOLVED REFLECTANCE; PENETRATION DEPTH; BLOOD-FLOW; HUMAN HEAD; TISSUE; DENSITY; LIGHT; OSTEOPOROSIS; TOMOGRAPHY; ABSORPTION Tissues Tomography, Optical Coherence Tomography, Optical Coherence - instrumentation Tomography, Optical Coherence - methods Trochanter Ulna Ulna - diagnostic imaging Ulna - metabolism Àrees temàtiques de la UPC Àrees temàtiques de la UPC::Matemàtiques i estadística::Investigació operativa Italy Spain
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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