Expression of microRNAs and Other Small RNAs in Prefrontal Cortex in Schizophrenia, Bipolar Disorder and Depressed Subjects

Because of the role played by miRNAs in post-transcriptional regulation of an array of genes, their impact in neuropsychiatric disease pathophysiology has increasingly been evident. In the present study, we assessed microRNA expression in prefrontal cortex (Brodmann area 10) of a well-characterized...

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Veröffentlicht in:	PloS one Jg. 9; H. 1; S. e86469
Hauptverfasser:	Smalheiser, Neil R., Lugli, Giovanni, Zhang, Hui, Rizavi, Hooriyah, Cook, Edwin H., Dwivedi, Yogesh
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 27.01.2014 Public Library of Science (PLoS)
Schlagworte:	Base Sequence Biology Biosynthesis Bipolar disorder Bipolar Disorder - genetics Bipolar Disorder - metabolism Brain research Brodmann's area Cohort Studies Comparative analysis Consortia Depression - genetics Depression - metabolism Diagnostic systems Enrichment Epigenetics Female Gene expression Gene Expression Regulation - genetics Gene regulation Gene sequencing Genes Genetic aspects Genetic transcription Genomes High-Throughput Nucleotide Sequencing Humans Male Medical research Medicine Medicine, Experimental Mental depression Mental disorders MicroRNA MicroRNAs MicroRNAs - metabolism miRNA Molecular Sequence Data Neuropathology Neurophysiology Non-coding RNA Nucleotide sequence Polymerase chain reaction Post-transcription Prefrontal cortex Prefrontal Cortex - metabolism Psychiatry Reverse Transcriptase Polymerase Chain Reaction Ribonucleic acid RNA Schizophrenia Schizophrenia - genetics Schizophrenia - metabolism Sequence Analysis, DNA Statistics, Nonparametric Studies Suicidal Ideation Suicide Synaptosomes Synaptosomes - metabolism United States > US Illinois Chicago Illinois
ISSN:	1932-6203, 1932-6203
Online-Zugang:	Volltext
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