mRNA-Seq of Single Prostate Cancer Circulating Tumor Cells Reveals Recapitulation of Gene Expression and Pathways Found in Prostate Cancer

Circulating tumor cells (CTC) mediate metastatic spread of many solid tumors and enumeration of CTCs is currently used as a prognostic indicator of survival in metastatic prostate cancer patients. Some evidence suggests that it is possible to derive additional information about tumors from expressio...

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Veröffentlicht in:	PloS one Jg. 7; H. 11; S. e49144
Hauptverfasser:	Cann, Gordon M., Gulzar, Zulfiqar G., Cooper, Samantha, Li, Robin, Luo, Shujun, Tat, Mai, Stuart, Sarah, Schroth, Gary, Srinivas, Sandhya, Ronaghi, Mostafa, Brooks, James D., Talasaz, AmirAli H.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 07.11.2012 Public Library of Science (PLoS)
Schlagworte:	Analysis Apoptosis Biology Biomarkers, Tumor - blood Blood Cancer Cancer genetics Cancer metastasis Cell Line, Tumor Engineering Enumeration Gene expression Gene Expression Regulation, Neoplastic Human subjects Humans Kinases Leukocytes Male Medicine Messenger RNA Metabolic Networks and Pathways Metastases Metastasis Neoplasm Metastasis - genetics Neoplasm Metastasis - pathology Neoplastic Cells, Circulating - metabolism Neoplastic Cells, Circulating - pathology Patients Prognosis Prostate cancer Prostatic Neoplasms - blood Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology Ribonucleic acid RNA RNA, Messenger - blood RNA, Messenger - genetics Sequence Alignment Sequence Analysis, RNA Solid tumors Transcription Transcription (Genetics) Tumor cells Tumors Urology United States > US California
ISSN:	1932-6203, 1932-6203
Online-Zugang:	Volltext
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