Chemopreventive effect of cactus Opuntia ficus indica on oxidative stress and genotoxicity of aflatoxin B1

Background Aflatoxin B1 (AFB1) is potent hepatotoxic and hepatocarcinogenic agent. In aflatoxicosis, oxidative stress is a common mechanism contributing to initiation and progression of hepatic damage. The aim of this work was to evaluate the hepatoprotective effect of cactus cladode extract (CCE) o...

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Bibliographic Details
Published in:	Nutrition & metabolism Vol. 8; no. 1; pp. 73 - 372
Main Authors:	Brahmi, Dalel, Bouaziz, Chayma, Ayed, Yousra, Ben Mansour, Hédi, Zourgui, Lazhar, Bacha, Hassen
Format:	Journal Article
Language:	English
Published:	London BioMed Central 18.10.2011 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	adults aflatoxicosis Aflatoxin B1 Aflatoxins antioxidants Apoptosis cacti and succulents Cactus Cancer chemoprevention chromosome aberrations Clinical Nutrition Development and progression DNA fragmentation gene expression regulation genes Genotoxicity heat shock proteins Hepatopretective hepatoprotective effect hepatotoxicity intraperitoneal injection liver Liver cancer liver protein malondialdehyde Medicine Medicine & Public Health Metabolic Diseases mice Opuntia ficus-indica Oxidative Stress Physiological aspects Proteins Risk factors Rodents Tumor proteins Tunisia Aflatoxin B1 Hepatopretective Oxidative Stress Cactus Genotoxicity
ISSN:	1743-7075, 1743-7075
Online Access:	Get full text
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