The potential for circular dichroism as an additional facile and sensitive method of monitoring low-molecular-weight heparins and heparinoids

The ultraviolet circular dichroism (CD) spectra of commercial low-molecular-weight heparins, heparinoids and other anticoagulant preparations have been recorded between 180 and 260 nm. Principal component analysis of the spectra allowed their differentiation into a number of groups related to the me...

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Bibliographic Details
Published in:	Thrombosis and haemostasis Vol. 102; no. 5; p. 874
Main Authors:	Rudd, Timothy R, Skidmore, Mark A, Guimond, Scott E, Holman, Joseph, Turnbull, Jeremy E, Lauder, Robert M, Fernig, David G, Yates, Edwin A
Format:	Journal Article
Language:	English
Published:	Germany 01.11.2009
Subjects:	Animals Anticoagulants - chemistry Anticoagulants - isolation & purification Cattle Circular Dichroism Drug Monitoring - methods Factor Analysis, Statistical Glycosaminoglycans - chemistry Heparin, Low-Molecular-Weight - chemistry Heparin, Low-Molecular-Weight - isolation & purification Heparinoids - chemistry Heparinoids - classification Heparinoids - isolation & purification Molecular Structure Multivariate Analysis Principal Component Analysis Swine
ISSN:	0340-6245, 2567-689X, 2567-689X
Online Access:	Get more information
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