Thyroid autoimmunity in relation to islet autoantibodies and HLA-DQ genotype in newly diagnosed type 1 diabetes in children and adolescents

Aims/hypothesis The aim of this work was to investigate, in children newly diagnosed with type 1 diabetes: (1) the prevalence of autoantibodies against thyroid peroxidase (TPOAb) and thyroglobulin (TGAb); and (2) the association between TPOAb, TGAb or both, with either islet autoantibodies or HLA-DQ...

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Bibliographic Details
Published in:	Diabetologia Vol. 56; no. 8; pp. 1735 - 1742
Main Authors:	Jonsdottir, B., Andersson, C., Carlsson, A., Delli, A., Forsander, G., Ludvigsson, J., Marcus, C., Samuelsson, U., Örtqvist, E., Lernmark, Å., Ivarsson, S.-A., Larsson, H. Elding
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer Berlin Heidelberg 01.08.2013 Springer Springer Nature B.V
Subjects:	Adolescent Autoantibodies - immunology Autoimmune thyroid diseases Autoimmunity - genetics Autoimmunity - immunology Biological and medical sciences Child Child, Preschool Clinical Medicine Diabetes Diabetes mellitus Diabetes Mellitus, Type 1 - genetics Diabetes Mellitus, Type 1 - immunology Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinology and Diabetes Endocrinopathies Endokrinologi och diabetes Etiopathogenesis. Screening. Investigations. Target tissue resistance Female GAD65 autoantibodies Genotype Genotype & phenotype Haplotypes HLA genotype HLA-DQ Antigens - immunology Hospitals Human Physiology Humans IA-2 autoantibodies Infant Insulin Insulin autoantibodies Internal Medicine Investigations Klinisk medicin Male Medical and Health Sciences Medical sciences MEDICIN Medicin och hälsovetenskap MEDICINE Medicine & Public Health Metabolic Diseases Non tumoral diseases. Target tissue resistance. Benign neoplasms Pediatrics Proteins Teenagers Thyroglobulin antibodies Thyroid diseases Thyroid Gland - immunology Thyroid peroxidase antibodies Thyroid. Thyroid axis (diseases) Type 1 diabetes ZnT8 autoantibodies Sweden Thyroid peroxidase antibodies Thyroglobulin antibodies Type 1 diabetes Diabetes mellitus IA-2 autoantibodies Autoimmune thyroid diseases HLA genotype Insulin autoantibodies ZnT8 autoantibodies GAD65 autoantibodies Endocrinopathy Autoimmunity HLA-System Pancreatic hormone Endocrine gland Autoimmune disease Thyroid gland Peroxidase Child Human Immunopathology Enzyme Antibody Thyroid diseases Autoantibody Genotype Insulin Peroxidases Thyroglobulin Adolescent Thyroid hormone Oxidoreductases
ISSN:	0012-186X, 1432-0428, 1432-0428
Online Access:	Get full text
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