Experimental and Computational Evidence for the Mechanism of Intradiol Catechol Dioxygenation by Non-Heme Iron(III) Complexes

Catechol intradiol dioxygenation is a unique reaction catalyzed by iron‐dependent enzymes and non‐heme iron(III) complexes. The mechanism by which these systems activate dioxygen in this important metabolic process remains controversial. Using a combination of kinetic measurements and computational...

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Bibliographic Details
Published in:	Chemistry : a European journal Vol. 20; no. 48; pp. 15686 - 15691
Main Authors:	Jastrzebski, Robin, Quesne, Matthew G., Weckhuysen, Bert M., de Visser, Sam P., Bruijnincx, Pieter C. A.
Format:	Journal Article
Language:	English
Published:	Weinheim WILEY-VCH Verlag 24.11.2014 WILEY‐VCH Verlag Wiley Subscription Services, Inc
Subjects:	biomimetic models Bonding Carbon Catalysis Catechol Catechols Chemical reactions Chemistry Cleavage Communications Computation Computers, Molecular density functional theory enzyme models Ferric Compounds - chemistry Iron Kinetics Models, Molecular Molecular Structure Oxygen - chemistry reactivity biomimetic models reactivity kinetics enzyme models density functional theory
ISSN:	0947-6539, 1521-3765, 1521-3765
Online Access:	Get full text
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