A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

Hugh Watkins, Sekar Kathiresan, Ruth McPherson, Martin Farrall and colleagues report the results of a large genome-wide association meta-analysis of coronary artery disease based on 1000 Genomes imputation. They identify ten new risk loci and show that susceptibility to this disease is largely deter...

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Vydáno v:	Nature genetics Ročník 47; číslo 10; s. 1121 - 1130
Hlavní autoři:	Nikpay, Majid, Goel, Anuj, Won, Hong-Hee, Hall, Leanne M, Willenborg, Christina, Kanoni, Stavroula, Kyriakou, Theodosios, Nelson, Christopher P, Harris, Tamara B, Hazen, Stanley L, Hengstenberg, Christian, Hofman, Albert, Ingelsson, Erik, Iribarren, Carlos, Jukema, J Wouter, Karhunen, Pekka J, Kim, Bong-Jo, Webb, Thomas R, Kullo, Iftikhar J, Loos, Ruth JF, Melander, Olle, Metspalu, Andres, Palmer, Colin N, Quertermous, Thomas, Rader, Daniel J, Zeng, Lingyao, Ridker, Paul M, Roberts, Robert, Schwartz, Stephen M, Stewart, Alexandre F, Stott, David J, Thiery, Joachim, Dehghan, Abbas, Zalloua, Pierre A, O'Donnell, Christopher J, Thompson, John R, Erdmann, Jeanette, Clarke, Robert, Kathiresan, Sekar, McPherson, Ruth, Alver, Maris, Deloukas, Panos, Samani, Nilesh J, Farrall, Martin, Auro, Kirsi, Bjonnes, Andrew, Chasman, Daniel I, Chen, Shufeng, d, Ian, Franceschini, Nora, Gieger, Christian, Grace, Christopher, Gustafsson, Stefan, Huang, Jie, Kim, Yun Kyoung, Lau, King Wai, Lyytikäinen, Leo-Pekka, Morrison, Alanna C, Pervjakova, Natalia, Rose, Lynda M, Salfati, Elias, Saxena, Richa, Scholz, Markus, Tikkanen, Emmi, Uitterlinden, Andre, Zhang, Weihua, de Andrade, Mariza, van Zuydam, Natalie R, Dedoussis, George, Frossard, Philippe, Gauguier, Dominique, Goodall, Alison H, Gottesman, Omri, Haber, Marc, Huang, Jianfeng, König, Inke R, Lannfelt, Lars, Lind, Lars, Lindgren, Cecilia M, Magnusson, Patrik K, Mallick, Nadeem H, Meitinger, Thomas, Memon, Fazal-ur-Rehman, Morris, Andrew P, Nieminen, Markku S, Rallidis, Loukianos S, Rasheed, Asif, Sinisalo, Juha, Stirrups, Kathleen E, Wang, Laiyuan, Ardissino, Diego, Boerwinkle, Eric, Bottinger, Erwin P, Buring, Julie E, Chambers, John C, Cupples, L Adrienne, Danesh, John, Demuth, Ilja, Gudnason, Roberto, Hamsten, Anders
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	New York Nature Publishing Group US 01.10.2015 Nature Publishing Group
Témata:	45/43 631/208/205/2138 692/699/75/2/1674 Agriculture Analysis Animal Genetics and Genomics Basic Medicine Biomedicine Cancer Research Cardiology and Cardiovascular Disease Cardiovascular disease Cardiovascular research Clinical Medicine Coronary heart disease Coronary vessels Development and progression Gene Function Gene loci Genetic aspects Genetic research Genetic susceptibility Genetic variance Genomes Haplotypes Health aspects Heart attacks Heterogeneity Human Genetics Kardiologi och kardiovaskulära sjukdomar Klinisk medicin Medical and Health Sciences Medical Genetics and Genomics (including Gene Therapy) Medicin och hälsovetenskap Medicinsk genetik och genomik (Här ingår: Genterapi) Medicinska och farmaceutiska grundvetenskaper Meta-analysis Ratios Single nucleotide polymorphisms Vein & artery diseases
ISSN:	1061-4036, 1546-1718, 1546-1718
On-line přístup:	Získat plný text
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