Plasma metabolites to profile pathways in noncommunicable disease multimorbidity

Multimorbidity, the simultaneous presence of multiple chronic conditions, is an increasing global health problem and research into its determinants is of high priority. We used baseline untargeted plasma metabolomics profiling covering >1,000 metabolites as a comprehensive readout of human physio...

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Vydáno v:	Nature medicine Ročník 27; číslo 3; s. 471 - 479
Hlavní autoři:	Pietzner, Maik, Stewart, Isobel D., Raffler, Johannes, Khaw, Kay-Tee, Michelotti, Gregory A., Kastenmüller, Gabi, Wareham, Nicholas J., Langenberg, Claudia
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	New York Nature Publishing Group US 01.03.2021 Nature Publishing Group
Témata:	631/114/2164 631/114/2401 631/67 692/499 692/53 Aged Biomedical and Life Sciences Biomedicine Cancer Research Chronic conditions Chronic diseases Chronic illnesses Cohort Studies Comorbidity Development and progression Electronic health records Electronic medical records Female Global health Glucose metabolism Health aspects Humans Identification and classification Infectious Diseases Inflammation Lipid metabolism Lipids Male Metabolic Diseases Metabolites Metabolome Metabolomics Microorganisms Middle Aged Molecular Medicine Multimorbidity Neurosciences Noncommunicable Diseases Physiological aspects Plasma - metabolism Public health Risk analysis Risk factors United Kingdom
ISSN:	1078-8956, 1546-170X, 1546-170X
On-line přístup:	Získat plný text
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