Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall

Photoreceptors for visual perception, phototaxis or light avoidance are typically clustered in eyes or related structures such as the Bolwig organ of Drosophila larvae. Unexpectedly, we found that the class IV dendritic arborization neurons of Drosophila melanogaster larvae respond to ultraviolet, v...

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Published in:Nature (London) Vol. 468; no. 7326; pp. 921 - 926
Main Authors: Xiang, Yang, Yuan, Quan, Vogt, Nina, Looger, Loren L., Jan, Lily Yeh, Jan, Yuh Nung
Format: Journal Article
Language:English
Published: London Nature Publishing Group UK 16.12.2010
Nature Publishing Group
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ISSN:0028-0836, 1476-4687, 1476-4687
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Abstract Photoreceptors for visual perception, phototaxis or light avoidance are typically clustered in eyes or related structures such as the Bolwig organ of Drosophila larvae. Unexpectedly, we found that the class IV dendritic arborization neurons of Drosophila melanogaster larvae respond to ultraviolet, violet and blue light, and are major mediators of light avoidance, particularly at high intensities. These class IV dendritic arborization neurons, which are present in every body segment, have dendrites tiling the larval body wall nearly completely without redundancy. Dendritic illumination activates class IV dendritic arborization neurons. These novel photoreceptors use phototransduction machinery distinct from other photoreceptors in Drosophila and enable larvae to sense light exposure over their entire bodies and move out of danger. How fruitfly maggots avoid sunlight Light sensing outside the eyes is common in many animals, usually confined to specialized organs. But now the entire body wall of the Drosophila fruitfly larva has been found to be blanketed with blue and ultraviolet light-sensing neuronal dendrites, which are essential for the maggot's innate light-avoidance behaviour. The phototransduction machinery used by these neurons is distinct from other Drosophila photoreceptor molecules, but similar to a system identified in nematode neurons. Light sensing outside the eyes is common in many animals but is usually confined to specialized organs. Here, the entire body wall of the fruitfly larva is found to be tiled with blue- and ultraviolet-light sensing neuronal dendrites, which are essential for the larva's innate light-avoidance behaviour. The phototransduction machinery used by these neurons is distinct from other Drosophila photoreceptor molecules but similar to a system recently identified in nematode neurons.
AbstractList Photoreceptors for visual perception, phototaxis or light avoidance are typically clustered in eyes or related structures such as the Bolwig organ of Drosophila larvae. Unexpectedly, we found that the class IV dendritic arborization neurons of Drosophila melanogaster larvae respond to ultraviolet, violet and blue light, and are major mediators of light avoidance, particularly at high intensities. These class IV dendritic arborization neurons, which are present in every body segment, have dendrites tiling the larval body wall nearly completely without redundancy. Dendritic illumination activates class IV dendritic arborization neurons. These novel photoreceptors use phototransduction machinery distinct from other photoreceptors in Drosophila and enable larvae to sense light exposure over their entire bodies and move out of danger.
Photoreceptors for visual perception, phototaxis or light avoidance are typically clustered in eyes or related structures such as the Bolwig organ of Drosophila larvae. Unexpectedly, we found that the class IV dendritic arborization neurons of Drosophila melanogaster larvae respond to ultraviolet, violet and blue light, and are major mediators of light avoidance, particularly at high intensities. These class IV dendritic arborization neurons, which are present in every body segment, have dendrites tiling the larval body wall nearly completely without redundancy. Dendritic illumination activates class IV dendritic arborization neurons. These novel photoreceptors use phototransduction machinery distinct from other photoreceptors in Drosophila and enable larvae to sense light exposure over their entire bodies and move out of danger.Photoreceptors for visual perception, phototaxis or light avoidance are typically clustered in eyes or related structures such as the Bolwig organ of Drosophila larvae. Unexpectedly, we found that the class IV dendritic arborization neurons of Drosophila melanogaster larvae respond to ultraviolet, violet and blue light, and are major mediators of light avoidance, particularly at high intensities. These class IV dendritic arborization neurons, which are present in every body segment, have dendrites tiling the larval body wall nearly completely without redundancy. Dendritic illumination activates class IV dendritic arborization neurons. These novel photoreceptors use phototransduction machinery distinct from other photoreceptors in Drosophila and enable larvae to sense light exposure over their entire bodies and move out of danger.
Photoreceptors for visual perception, phototaxis or light avoidance are typically clustered in eyes or related structures such as the Bolwig organ of Drosophila larvae. Unexpectedly, we found that the class IV dendritic arborization neurons of Drosophila melanogaster larvae respond to ultraviolet, violet and blue light, and are major mediators of light avoidance, particularly at high intensities. These class IV dendritic arborization neurons, which are present in every body segment, have dendrites tiling the larval body wall nearly completely without redundancy. Dendritic illumination activates class IV dendritic arborization neurons. These novel photoreceptors use phototransduction machinery distinct from other photoreceptors in Drosophila and enable larvae to sense light exposure over their entire bodies and move out of danger. [PUBLICATION ABSTRACT]
Photoreceptors for visual perception, phototaxis or light avoidance are typically clustered in eyes or related structures such as the Bolwig organ of Drosophila larvae. Unexpectedly, we found that the class IV dendritic arborization neurons of Drosophila melanogaster larvae respond to ultraviolet, violet and blue light, and are major mediators of light avoidance, particularly at high intensities. These class IV dendritic arborization neurons, which are present in every body segment, have dendrites tiling the larval body wall nearly completely without redundancy. Dendritic illumination activates class IV dendritic arborization neurons. These novel photoreceptors use phototransduction machinery distinct from other photoreceptors in Drosophila and enable larvae to sense light exposure over their entire bodies and move out of danger. How fruitfly maggots avoid sunlight Light sensing outside the eyes is common in many animals, usually confined to specialized organs. But now the entire body wall of the Drosophila fruitfly larva has been found to be blanketed with blue and ultraviolet light-sensing neuronal dendrites, which are essential for the maggot's innate light-avoidance behaviour. The phototransduction machinery used by these neurons is distinct from other Drosophila photoreceptor molecules, but similar to a system identified in nematode neurons. Light sensing outside the eyes is common in many animals but is usually confined to specialized organs. Here, the entire body wall of the fruitfly larva is found to be tiled with blue- and ultraviolet-light sensing neuronal dendrites, which are essential for the larva's innate light-avoidance behaviour. The phototransduction machinery used by these neurons is distinct from other Drosophila photoreceptor molecules but similar to a system recently identified in nematode neurons.
Audience Academic
Author Vogt, Nina
Yuan, Quan
Looger, Loren L.
Jan, Lily Yeh
Jan, Yuh Nung
Xiang, Yang
AuthorAffiliation 3 Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, Virginia 20147, USA
1 Howard Hughes Medical Institute, Departments of Physiology, Biochemistry, and Biophysics, University of California San Francisco, San Francisco, California 94158, USA
2 Center for Developmental Genetics, New York University, New York, New York 10003, USA
AuthorAffiliation_xml – name: 1 Howard Hughes Medical Institute, Departments of Physiology, Biochemistry, and Biophysics, University of California San Francisco, San Francisco, California 94158, USA
– name: 2 Center for Developmental Genetics, New York University, New York, New York 10003, USA
– name: 3 Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, Virginia 20147, USA
Author_xml – sequence: 1
  givenname: Yang
  surname: Xiang
  fullname: Xiang, Yang
  organization: Departments of Physiology, Howard Hughes Medical Institute, Biochemistry, and Biophysics, University of California San Francisco
– sequence: 2
  givenname: Quan
  surname: Yuan
  fullname: Yuan, Quan
  organization: Departments of Physiology, Howard Hughes Medical Institute, Biochemistry, and Biophysics, University of California San Francisco
– sequence: 3
  givenname: Nina
  surname: Vogt
  fullname: Vogt, Nina
  organization: Center for Developmental Genetics, New York University
– sequence: 4
  givenname: Loren L.
  surname: Looger
  fullname: Looger, Loren L.
  organization: Howard Hughes Medical Institute, Janelia Farm Research Campus
– sequence: 5
  givenname: Lily Yeh
  surname: Jan
  fullname: Jan, Lily Yeh
  organization: Departments of Physiology, Howard Hughes Medical Institute, Biochemistry, and Biophysics, University of California San Francisco
– sequence: 6
  givenname: Yuh Nung
  surname: Jan
  fullname: Jan, Yuh Nung
  email: yuhnung.jan@ucsf.edu
  organization: Departments of Physiology, Howard Hughes Medical Institute, Biochemistry, and Biophysics, University of California San Francisco
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https://www.ncbi.nlm.nih.gov/pubmed/21068723$$D View this record in MEDLINE/PubMed
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Snippet Photoreceptors for visual perception, phototaxis or light avoidance are typically clustered in eyes or related structures such as the Bolwig organ of...
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Aggregation Database
Index Database
Enrichment Source
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StartPage 921
SubjectTerms 631/378
631/601/18
631/80
639/638/439/944
Animal Structures - cytology
Animal Structures - metabolism
Animal Structures - radiation effects
Animals
Avoidance Learning - physiology
Avoidance Learning - radiation effects
Behavior
Biological and medical sciences
Cells, Cultured
Dermis - metabolism
Dermis - radiation effects
Drosophila
Drosophila melanogaster - anatomy & histology
Drosophila melanogaster - cytology
Drosophila melanogaster - physiology
Drosophila melanogaster - radiation effects
Drosophila Proteins - metabolism
Eye and associated structures. Visual pathways and centers. Vision
Eyes & eyesight
Fundamental and applied biological sciences. Psychology
Humanities and Social Sciences
Insects
Ion Channels
Larva - anatomy & histology
Larva - cytology
Larva - radiation effects
Larvae
Light
Light Signal Transduction - radiation effects
multidisciplinary
Neurons
Neurons - physiology
Neurons - radiation effects
Photoreception
Photoreceptor Cells, Invertebrate - metabolism
Photoreceptor Cells, Invertebrate - radiation effects
Photoreceptors
Physiological aspects
Receptors, Cell Surface - metabolism
Science
Science (multidisciplinary)
Sensory perception
TRPA1 Cation Channel
TRPC Cation Channels - metabolism
Vertebrates: nervous system and sense organs
Title Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall
URI https://link.springer.com/article/10.1038/nature09576
https://www.ncbi.nlm.nih.gov/pubmed/21068723
https://www.proquest.com/docview/820913429
https://www.proquest.com/docview/818645087
https://pubmed.ncbi.nlm.nih.gov/PMC3026603
Volume 468
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