The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease

Long non-coding RNAs (lncRNAs) are transcripts with low protein-coding potential that represent a large proportion of the transcriptional output of the cell. Many lncRNAs exhibit features indicative of functionality including tissue-restricted expression, localization to distinct subcellular structu...

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Vydáno v:	Philosophical transactions of the Royal Society of London. Series B. Biological sciences Ročník 369; číslo 1652
Hlavní autoři:	Roberts, Thomas C, Morris, Kevin V, Wood, Matthew J A
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England 26.09.2014
Témata:	Brain - metabolism Brain - physiology Epigenesis, Genetic - genetics Epigenesis, Genetic - physiology Humans Nervous System - growth & development Nervous System Diseases - genetics Nervous System Diseases - physiopathology RNA, Long Noncoding - genetics RNA, Long Noncoding - physiology neurodegeneration long non-coding RNA neurodevelopment brain epigenetics
ISSN:	1471-2970, 1471-2970
On-line přístup:	Zjistit podrobnosti o přístupu
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