Stereotactic ablative radiotherapy for the comprehensive treatment of 1–3 Oligometastatic tumors (SABR-COMET-3): study protocol for a randomized phase III trial

Background A recent randomized phase II trial evaluated stereotactic ablative radiotherapy (SABR) in a group of patients with a small burden of oligometastatic disease (mostly with 1–3 metastatic lesions), and found that SABR was associated with a significant improvement in progression-free survival...

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Bibliographic Details
Published in:	BMC cancer Vol. 20; no. 1; pp. 380 - 12
Main Authors:	Olson, Robert, Mathews, Lindsay, Liu, Mitchell, Schellenberg, Devin, Mou, Benjamin, Berrang, Tanya, Harrow, Stephen, Correa, Rohann J. M., Bhat, Vasudeva, Pai, Howard, Mohamed, Islam, Miller, Stacy, Schneiders, Famke, Laba, Joanna, Wilke, Derek, Senthi, Sashendra, Louie, Alexander V., Swaminath, Anand, Chalmers, Anthony, Gaede, Stewart, Warner, Andrew, de Gruijl, Tanja D., Allan, Alison, Palma, David A.
Format:	Journal Article
Language:	English
Published:	London BioMed Central 05.05.2020 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Abdomen Adult Aged Aged, 80 and over Antigens Biomedical and Life Sciences Biomedicine Biopsy Breast Cancer Cancer metastasis Cancer Research Cancer therapies Care and treatment Chemotherapy Clinical trials Clinical Trials, Phase III as Topic Disease Progression Dose Fractionation, Radiation Female Four-Dimensional Computed Tomography - methods Health Promotion and Disease Prevention Histology Humans Lesions Male Medical and radiation oncology Medicine/Public Health Metastases Metastasis Middle Aged Multicenter Studies as Topic Neoplasm Metastasis Neoplasms - pathology Neoplasms - surgery Neoplastic Cells, Circulating - pathology Oligometastases Oncology Patient Selection Patients Prostate Quality of Life Radiation therapy Radiosurgery - methods Radiotherapy Randomized Controlled Trials as Topic Spinal cord Stereotactic radiotherapy Study Protocol Surgical Oncology Survival Survival Rate Toxicity Treatment Outcome Tumor cells Tumors Young Adult Oligometastases Survival Stereotactic radiotherapy Quality of life Cancer
ISSN:	1471-2407, 1471-2407
Online Access:	Get full text
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