Relation of Vigorous Exercise to Risk of Atrial Fibrillation

Limited data suggest that athletes may have a higher risk of developing atrial fibrillation (AF); however, there has been no large prospective assessment of the relation between vigorous exercise and AF. Logistic regression analyses stratified by time were used to assess the association between freq...

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Vydané v:The American journal of cardiology Ročník 103; číslo 11; s. 1572 - 1577
Hlavní autori: Aizer, Anthony, Gaziano, J. Michael, Cook, Nancy R., Manson, Joann E., Buring, Julie E., Albert, Christine M.
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: New York, NY Elsevier Inc 01.06.2009
Elsevier
Elsevier Limited
Predmet:
Adult
Age Factors
Aged
Aged, 80 and over
Atrial Fibrillation - epidemiology
Biological and medical sciences
Body Mass Index
Cardiac arrhythmia
Cardiac dysrhythmias
Cardiology
Cardiology. Vascular system
Cardiovascular
Effect Modifier, Epidemiologic
Exercise
Heart
Humans
Life Style
Logistic Models
Male
Medical sciences
Mens health
Middle Aged
Prospective Studies
Regression analysis
Risk Assessment
Risk factors
Physical exercise
Arrhythmia
Heart disease
Atrial fibrillation
Risk factor
Cardiovascular disease
Exercise tolerance test
Risk
Circulatory system
Cardiology
Excitability disorder
ISSN:0002-9149, 1879-1913, 1879-1913
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Shrnutí:Limited data suggest that athletes may have a higher risk of developing atrial fibrillation (AF); however, there has been no large prospective assessment of the relation between vigorous exercise and AF. Logistic regression analyses stratified by time were used to assess the association between frequency of vigorous exercise and risk of developing AF in 16,921 apparently healthy men in the Physicians' Health Study. During 12 years of follow-up, 1,661 men reported developing AF. With increasing frequency of vigorous exercise (0, 1, 1 to 2, 3 to 4, 5 to 7 days/week), multivariate relative risks for the full cohort were 1.0 (referent), 0.90, 1.09, 1.04, and 1.20 (p = 0.04). This risk was not significantly increased when exercise habits were updated or in models excluding variables that may be in the biological pathway through which exercise influences AF risk. In subgroup analyses, this increased risk was observed only in men <50 years of age (1.0, 0.94, 1.20, 1.05, 1.74, p <0.01) and joggers (1.0, 0.91, 1.03, 1.30, 1.53, p <0.01), where risks remained increased in all analyses. In conclusion, frequency of vigorous exercise was associated with an increased risk of developing AF in young men and joggers. This risk decreased as the population aged and was offset by known beneficial effects of vigorous exercise on other AF risk factors.
Bibliografia:ObjectType-Article-1
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ISSN:0002-9149
1879-1913
1879-1913
DOI:10.1016/j.amjcard.2009.01.374