Accuracy of Immunodiagnostic Tests for Active Tuberculosis Using Single and Combined Results: A Multicenter TBNET-Study

The clinical application of IFN-gamma release assays (IGRAs) has recently improved the diagnosis of latent tuberculosis infection. In a multicenter study of the Tuberculosis Network European Trialsgroup (TBNET) we aimed to ascertain in routine clinical practice the accuracy of a novel assay using se...

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Bibliographic Details
Published in:	PloS one Vol. 3; no. 10; p. e3417
Main Authors:	Goletti, Delia, Stefania, Carrara, Butera, Ornella, Amicosante, Massimo, Ernst, Martin, Sauzullo, Ilaria, Vullo, Vincenzo, Cirillo, Daniela, Borroni, Emanuele, Markova, Roumiana, Drenska, Roumiana, Dominguez, José, Latorre, Irene, Angeletti, Claudio, Navarra, Assunta, Petrosillo, Nicola, Lauria, Francesco Nicola, Ippolito, Giuseppe, Migliori, Giovanni Battista, Lange, Christoph, Girardi, Enrico
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 15.10.2008 Public Library of Science (PLoS)
Subjects:	Adult Antigens Antigens, Bacterial - analysis Assaying Blood tests Clinical medicine Diagnosis Enzymes Epidemiology Female Gold Health aspects Hospitals Humans Immune response Immunologic Tests - methods Immunologic Tests - standards Immunology Infections Infectious Diseases Infectious Diseases/Epidemiology and Control of Infectious Diseases Infectious Diseases/Respiratory Infections Interferon Lymphocytes Male Medical diagnosis Medical tests Middle Aged Mycobacterium tuberculosis Mycobacterium tuberculosis - immunology Pathogens Peptides Prospective Studies Reproducibility of Results Sensitivity Sensitivity and Specificity Skin tests T cell receptors Tropical diseases Tuberculin Tuberculin Test - standards Tuberculosis Tuberculosis - diagnosis γ-Interferon Italy
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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