Delineating morbillivirus entry, dissemination and airborne transmission by studying in vivo competition of multicolor canine distemper viruses in ferrets

Identification of cellular receptors and characterization of viral tropism in animal models have vastly improved our understanding of morbillivirus pathogenesis. However, specific aspects of viral entry, dissemination and transmission remain difficult to recapitulate in animal models. Here, we used...

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Veröffentlicht in:	PLoS pathogens Jg. 13; H. 5; S. e1006371
Hauptverfasser:	de Vries, Rory D., Ludlow, Martin, de Jong, Alwin, Rennick, Linda J., Verburgh, R. Joyce, van Amerongen, Geert, van Riel, Debby, van Run, Peter R. W. A., Herfst, Sander, Kuiken, Thijs, Fouchier, Ron A. M., Osterhaus, Albert D. M. E., de Swart, Rik L., Duprex, W. Paul
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 08.05.2017 Public Library of Science (PLoS)
Schlagworte:	Airborne infection Airborne infections Analysis Animal models Animals Biology and Life Sciences Cages Canine distemper Chlorocebus aethiops Coinfection Colleges & universities Color Competition Disease transmission Distemper Virus, Canine - physiology Epidemics Ferrets Fever Fluorescence Genes, Reporter In vivo methods and tests Infections Influenza Inoculation Lethargy Lymphocytes Lymphoid tissue Lymphopenia Measles Medicine and Health Sciences Morbillivirus - pathogenicity Morbillivirus - physiology Morbillivirus Infections - transmission Morbillivirus Infections - virology Paramyxoviruses Pathogenesis Peripheral blood Physiological aspects Proteins Receptors Receptors, Cell Surface - genetics Receptors, Cell Surface - metabolism Replication Research and Analysis Methods Respiratory syncytial virus Tissues Tropism Vero Cells Veterinary medicine Viral Load Virus Internalization Viruses Zoonoses United States > US Massachusetts
ISSN:	1553-7374, 1553-7366, 1553-7374
Online-Zugang:	Volltext
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