Cancer epigenetics: Moving forward

Defects in chromatin modifiers and remodelers have been described both for hematological and solid malignancies, corroborating and strengthening the role of epigenetic aberrations in the etiology of cancer. Furthermore, epigenetic marks-DNA methylation, histone modifications, chromatin remodeling, a...

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Veröffentlicht in:	PLoS genetics Jg. 14; H. 6; S. e1007362
Hauptverfasser:	Nebbioso, Angela, Tambaro, Francesco Paolo, Dell’Aversana, Carmela, Altucci, Lucia
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 07.06.2018 Public Library of Science (PLoS)
Schlagworte:	Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Biology Biology and life sciences Biomarkers, Tumor - genetics Breast cancer Cancer Cancer genetics Cancer research Cancer therapies Chromatin Chromatin Assembly and Disassembly - genetics Chromatin remodeling Consortia Deoxyribonucleic acid Disease Disease Progression DNA DNA methylation DNA Methylation - genetics Enzyme Inhibitors - pharmacology Enzyme Inhibitors - therapeutic use Enzymes - genetics Enzymes - metabolism Epigenesis, Genetic - drug effects Epigenetic inheritance Epigenetics Epigenomics - methods Etiology Forecasts and trends Gene expression Gene Expression Regulation, Neoplastic Genetic research Genomes Histone Code - genetics Humans Leukemia Medicine and Health Sciences MicroRNAs - genetics miRNA Molecular Targeted Therapy - methods Mutation Neoplasms - diagnosis Neoplasms - drug therapy Neoplasms - genetics Patients Prognosis Review Transcription factors Tumorigenesis Italy
ISSN:	1553-7404, 1553-7390, 1553-7404
Online-Zugang:	Volltext
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