Delayed Laboratory Response to COVID-19 Caused by Molecular Diagnostic Contamination

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) created an exceptional situation in which numerous laboratories in Europe simultaneously implemented SARS-CoV-2 diagnostics. These laboratories reported in February 2020 that commercial primer and probe batches for SARS-Co...

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Vydáno v:	Emerging infectious diseases Ročník 26; číslo 8; s. 1944 - 1946
Hlavní autoři:	Mögling, Ramona, Meijer, Adam, Berginc, Natasa, Bruisten, Sylvia, Charrel, Remi, Coutard, Bruno, Eckerle, Isabella, Enouf, Vincent, Hungnes, Olav, Korukluoglu, Gülay, Kossyvakis, Thanos, Mentis, Andreas, Molenkamp, Richard, Muradrasoli, Shaman, Papa, Anna, Pigny, Fiona, Thirion, Laurence, van der Werf, Sylvie, Reusken, Chantal
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States U.S. National Center for Infectious Diseases 01.08.2020 Centers for Disease Control and Prevention
Témata:	Acids Betacoronavirus - genetics Betacoronavirus - pathogenicity Clinical Laboratory Techniques - methods Clinical Laboratory Techniques - standards coronavirus disease Coronavirus Envelope Proteins Coronavirus Infections - diagnosis Coronavirus Infections - epidemiology Coronavirus Infections - virology Coronaviruses COVID-19 COVID-19 Testing Delayed Diagnosis delayed laboratory response Delayed Laboratory Response to COVID-19 Caused by Molecular Diagnostic Contamination Diagnosis Diagnostic Tests, Routine DNA Primers - analysis DNA Primers - chemical synthesis DNA Probes - analysis DNA Probes - chemical synthesis Europe - epidemiology Health aspects Humans Laboratories Laboratories - organization & administration Laboratories - standards Life Sciences Pandemics Pathology, Molecular Pneumonia, Viral - diagnosis Pneumonia, Viral - epidemiology Pneumonia, Viral - virology Reagent Kits, Diagnostic - standards Reagent Kits, Diagnostic - supply & distribution Research Letter Reverse Transcriptase Polymerase Chain Reaction - standards Reverse Transcriptase Polymerase Chain Reaction - statistics & numerical data RNA-Dependent RNA Polymerase - genetics SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome coronavirus 2 Viral Envelope Proteins - genetics viruses Europe Greece Sweden Netherlands Turkey France molecular diagnostics viruses delayed laboratory response Europe zoonoses coronaviruses respiratory infections contamination COVID-19 SARS-CoV-2 commercial nucleotide production severe acute respiratory syndrome coronavirus 2 coronavirus disease probes primers PCR
ISSN:	1080-6040, 1080-6059, 1080-6059
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Shrnutí:	The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) created an exceptional situation in which numerous laboratories in Europe simultaneously implemented SARS-CoV-2 diagnostics. These laboratories reported in February 2020 that commercial primer and probe batches for SARS-CoV-2 detection were contaminated with synthetic control material, causing delays of regional testing roll-out in various countries.
Bibliografie:	SourceType-Scholarly Journals-1 ObjectType-Correspondence-1 content type line 14 ObjectType-Article-1 ObjectType-Feature-2 content type line 23 PMCID: PMC7392437
ISSN:	1080-6040 1080-6059 1080-6059
DOI:	10.3201/eid2608.201843