Critically ill patients demonstrate large interpersonal variation in intestinal microbiota dysregulation: a pilot study

Purpose The intestinal microbiota has emerged as a virtual organ with essential functions in human physiology. Antibiotic-induced disruption of the microbiota in critically ill patients may have a negative influence on key energy resources and immunity. We set out to characterize the fecal microbiot...

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Bibliographic Details
Published in:	Intensive care medicine Vol. 43; no. 1; pp. 59 - 68
Main Authors:	Lankelma, Jacqueline M., van Vught, Lonneke A., Belzer, Clara, Schultz, Marcus J., van der Poll, Tom, de Vos, Willem M., Wiersinga, W. Joost
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer Berlin Heidelberg 01.01.2017 Springer Springer Nature B.V
Subjects:	Aged Aged, 80 and over Analysis Anesthesiology Anti-Bacterial Agents - adverse effects Antibiotics Biomarkers - analysis Clinical outcomes Critical Care Medicine Critical Illness Critically ill Emergency Medicine Feces Feces - microbiology Female Firmicutes Gastrointestinal Microbiome - drug effects Gut microbiota Humans Infection Intensive Intensive care Intensive care unit Male Medicine Medicine & Public Health Microbiota Microbiota (Symbiotic organisms) Middle Aged Mortality Netherlands Nosocomial infections Original Pain Medicine Patients Pediatrics Physiological aspects Pilot Projects Pneumology/Respiratory System Prospective Studies RNA Sepsis Sepsis - microbiology Software Netherlands Gut microbiota Sepsis Antibiotics Critically ill Intensive care unit
ISSN:	0342-4642, 1432-1238, 1432-1238
Online Access:	Get full text
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